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Computational Biologist in Single Cell Genomics

University of Oxford - Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital

Location: Oxford
Salary: £38,674 to £46,913 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 12th November 2024
Closes: 2nd December 2024
Job Ref: 176481

At the MRC WIMM Centre for Computational Biology (CCB), we work alongside scientists and clinicians to realise the potential of ‘big data’ in biology by exploiting complex information to make discoveries that benefit human health. The CCB encompasses an international team of over 40 computational biologists, working closely with 500 lab-based scientists and clinicians.

As part of a Wellcome Trust Collaborative award, applications are invited for a highly motivated individual to lead the analysis of single-cell gene expression and open chromatin profiling data, investigating transcriptional regulation during Drosophila Melanogaster brain development.

You will work closely with experimental collaborators within the Centre for Neural Circuits and Behaviour to answer important questions in developmental neuroscience. You will lead the analysis of single-cell RNAseq & ATACseq profiles from hundreds of thousands of neurons, representing the entire  fruit fly midbrain, from flies across development stages, to build a map of neuronal development and understand how sex-specific neuronal identity emerges from transcriptional programmes.

With a PhD or MSc in a quantitative discipline (e.g. bioinformatics, computational biology, physics, statistics, engineering or mathematics), you will have experience of working in a Linux environment and be proficient in Python and R. Excellent interpersonal and communication skills, with the ability to convey concepts to other scientists in different fields of research are essential. Experience in analysis of single cell gene expression data is highly desirable.

The position is available fixed-term until 31st March 2026, funded by the Wellcome Trust.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The closing date for this position is noon on 2 December 2024.  

Interviews will be held in December 2024. 

 

 

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