Postdoctoral Research Scientist

Department of Physiology, Anatomy and Genetics, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, South Parks Rd, Oxford, OX1 3QU

Contract type: Fixed term until October 2027

About us:

At the Department of Physiology Anatomy & Genetics (DPAG) we undertake discovery science where we reassemble physiological processes at the molecular, cellular, tissue and systems level of organisation. In so doing we provide a bridge to translational medicine, and interface between physical and life sciences. We are committed not only to innovative research and the highest standard of teaching, but also to creating an inclusive and supportive working environment.

Overview of the Role: We are seeking a Postdoctoral Research Scientist to join Dr. Becky Carlyle's lab as part of a collaborative project led by Professor Paul Harrison (Oxford Psychiatry). The project involves partnerships with Professor Carol Robinson (Oxford Chemistry), Dr. Thomas Hyde (Lieber Institute for Brain Development), and Professor Gary Stephens (Reading Pharmacology). The ideal candidate will have experience with membrane protein enrichment and preparation for mass-spectrometry analysis. A key focus will be developing assays to detect and quantify calcium channel conformations and interactomes, contributing to research on psychiatric disease mechanisms within a vibrant, international team. This is a 3-year position, available immediately.

Key Responsibilities:

• Optimize cellular and molecular approaches for membrane protein enrichment
• Develop and implement mass-spectrometry assays for protein analysis
• Manage academic research and related administrative tasks
• Refine scientific techniques and protocols, testing and analysing hypotheses
• Collaborate on scientific reports, journal articles, and presentations
• Operate specialist lab equipment and advise colleagues on protocols
• Represent the research group at meetings and seminars 

Selection Criteria:

• PhD/DPhil in bioscience (or near completion)
• Mass-spectrometry expertise, including sample preparation and data analysis
• Strong research, project management, and communication skills
• Experience with human brain tissue proteomics is a plus. 

What we offer:

Your wellbeing at work matters, so we offer a range of family friendly and financial benefits including:

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle and electric car loan schemes
• Employee Assistance Programme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

While this is a full-time role, we welcome applications from individuals who wish to be considered for flexible working arrangements.

How to apply:

Please provide a supporting statement outlining how you meet the selection criteria along with your CV, and the details of two referees as part of your online application.

The closing date for applications is 12 noon on Thursday 21st November.

Interviews are likely to take place during the week commencing 2nd December, and can be held face-to-face or on Microsoft Teams.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford. 

Informal enquiries about the role may be directed to the DPAG HR Team: hr@dpag.ox.ac.uk  

DPAG’s Statement of Inclusion:

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. Our policies, practices and Respectful Behaviours Framework underpin this commitment.

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