Postdoctoral Researcher – Signalling cross talks between cancer cells and infiltrating tumour monocytes and T cells

The Oxford Ludwig Institute for Cancer Research has an opportunity for a highly motivated Postdoctoral Researcher to join the group of Professor Xin Lu, on an exciting project which proposes to study the inside-out and outside-in signalling cross talks between esophageal cancer cells and immune cells.

You will design and lead an original research project to understanding of how cancer cells can recruit monocytes and under what condition monocytes can enhance the killing property of tumour infiltration CD8 T cells, and you will operate laboratory equipment used for all aspects of cell/molecular biology/biochemistry. You will be responsible for supervising and training junior staff in molecular biology and techniques including but not limited to single cell RNAseq and ATAC Seq. Other responsibilities will include interpreting results and presenting them to senior members of the groups, managing your own academic research and administrative activities, and participating in and contributing directly to scientific discussions with other members of the research group.

It is essential that you hold a PhD/DPhil (or close to completion) in experimental immunology, immunogenomics or cancer biology. You will have technical knowledge in one or more of immune killing, ex-vivo organoids or single cell/spatial -omics, and good communication skills, both written and verbal. It is essential you are able to organise and prioritise work efficiently whilst delivering results to the required standard and to an agreed schedule. A background working in tumour immunology would be highly desirable.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract for 36 months and is funded by Ludwig.

Research Grade 7: £38,674 - £46,913 with a discretionary range to £52,539 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year

Only applications received before 12 midday on 2 May 2025 will be considered. Please quote 178748 on all correspondence.

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