Research Assistant (Technical Analyst)

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
We are seeking an enthusiastic technical analyst to assist with the development of a unique online knowledge portal called CRISTAL (resourCe for Risk STratification research in Acute Leukaemia) which will host existing and future UK clinical trial datasets.

You will work as a member of the Leukaemia Research Cytogenomics Group (LRCG) in the Newcastle Translational & Clinical Research Institute at Newcastle University under the guidance of Professor Anthony Moorman and Dr Tim Newton. CRISTAL will comprise patient-level data including demographics, clinical features, treatment details, genetic/genomic characterisation, and outcome data. This unique resource will support in-depth analysis by members of the LRCG as well as approved collaborators from the leukaemia research community. In addition, an external interface will provide pertinent information to patients, clinicians, researchers, and the public.

The primary responsibility the post holder will be to assist our senior database developer to create robust pipelines to extract data from existing sources and then transform and map the data to the new structure used by CRISTAL. However, depending on the skills, experience and ambition of the successful applicant there is scope to be involved in business analysis (defining the look and feel of the system), software development (using dotnet C# (Blazor)) and using cloud-based services (e.g. AWS or Azure).

The post is part of the Cancer Research UK (CRUK) Experimental Medicine Award entitled “BIOINFORM: Biologically informed treatment decisions in acute leukaemia” award to Professor Moorman. The overall aim of the programme is to explore the genomic landscape of acute leukaemia and its association with clinical outcome. All the genomic datasets held by the LRCG are richly annotated with patient demographic, clinical, treatment and outcome; and correlating genetics with clinical features is a major part of our programme of research. You will work closely with internal and external collaborators who are experts in the biology and treatment of childhood and adult leukaemia to leverage our unique datasets to identify biomarkers and help improve the outcome of patients with acute leukaemia.

This is an excellent opportunity join a dynamic translational research group with a track record of improving patient diagnosis and management. You will have the opportunity to develop their technical expertise, learn new skills and progress to the next stage of their career. You will have a BSc/MSc in a relevant discipline (e.g. computing, maths, etc) or relevant experience processing and handling medical or biological data.

This appointment is on a fixed-term basis from 1st May 2025 until 30th April 2028.

Informal enquiries are encouraged and can be made to Professor Anthony Moorman anthony.moorman@newcastle.ac.uk.
Further Information about the Faculty can be found at: https://www.ncl.ac.uk/fms/.

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