Postdoctoral Research Assistant in Multiomic Analysis of Musculoskeletal Health and Pathology

This is an exciting opportunity for a postdoctoral research assistant to join the Soft Tissue Repair group led by Sarah Snelling. We are seeking an experienced, collaborative and enthusiastic postdoctoral scientist who will work to deliver bulk and single-cell resolution multi-omic datasets of soft and hard musculoskeletal tissues. These datasets will ultimately deliver novel mechanistic understanding of musculoskeletal health and disease, and prognostic and diagnostic indicators of musculoskeletal pathologies.

 

In this role you will carry out laboratory protocols that deliver multi-omic datasets of human musculoskeletal tissues and undertake computational analysis of multi-omic datasets of human musculoskeletal tissues. You will be adapting existing and developing new experimental protocols to robustly analyse archival and fresh musculoskeletal tissue samples. You will manage your own academic research and administrative activities, this involves small scale project management, to co-ordinate multiple aspects of your work to meet deadlines. In this position you will contribute ideas for new research projects including development of new grant proposals that support the ongoing research within the team and collaborate in the preparation of scientific reports and journal articles and occasionally present papers and posters.

 

You must hold a relevant PhD/DPhil (or be near completion), together with relevant experience, and possess demonstrable experience of generating bulk and/or single-cell resolution RNA sequencing data from fresh and archival or fixed tissue samples. You will have documented experience of the laboratory delivery of multiplex imaging datasets of tissue samples as well as significant laboratory experience of general methods including immunoassays and cell culture. You will have demonstrable experience, ability and practical success in end-to-end analysis of bulk, single-cell and/or spatial transcriptomic or proteomic datasets, including raw sequencing data processing, quality control, normalisation, data integration, and downstream analysis and interpretation. Experience of working with human musculoskeletal tissues, including tissue handing, processing for analysis, and in documentation and tissue tracking is desirable.

 

This is a full-time, fixed term position for 24 months. Part-time options may be considered with a minimum of 60% FTE.

 
The closing date for applications is 12 noon on 30 April 2025. Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application

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