Research Associate in Molecular Cell Biology

The role

A postdoc position is available to join the group of Dr Adam Grieve to investigate the molecular mechanisms of plasma membrane proteostasis. This is an exciting interdisciplinary project, primarily using mammalian cell lines and primary neurons to discover and dissect the molecular mechanisms that shape the neuronal cell surface proteome to maintain human health and prevent disease.

You will be a member of an enthusiastic team within a thriving cell biology research community investigating aspects of dynamics of proteins at membranes and intercellular signalling. The role will involve the day-to-day independent running of the project, collaboration with other research groups within the School, performing a range of research tasks and assisting with training and supervision of postgraduate members of the lab.

What will you be doing?

A major goal of the project is the discovery and investigation of new regulators of membrane protein proteostasis. The project will employ techniques such as protein biochemistry, molecular cell biology, quantitative proteomics, flow cytometry and various forms of light microscopy.

You should apply if

You are enthusiastic about fundamental molecular and cellular mechanisms and discovery-based approaches. You are interested in performing cell biological and/or proteomic screens.

A PhD in a relevant biological or biomedical science is essential (awarded or imminent). You should also have prior knowledge of molecular cell biology, particularly the investigation of membrane protein traffic, turnover and/or signalling. Previous experience of gene editing, flow cytometry, high throughput screens or neuronal cell culture are highly desirable. You will be highly organised, eager to develop new skills and committed to interacting respectfully with a broad range of colleagues.

The funds for this position are available for 18 months in the first instance. The position is available from June 2025, and the candidate would ideally start by July 2025.  Please visit the Lab website: grieve-lab.com for more information.

Additional information

Informal enquiries are welcomed, please contact Dr Adam Grieve adam.grieve@bristol.ac.uk; +44 (0)117 428 3752

Contract type: Open ended (fixed funding until 31/12/2026)

This advert will close at 23:59 UK time on Wednesday 23rd April 2025

Interviews will be held on Tuesday 3rd June 2025

Our strategy and mission

We recently launched our strategy to 2030 tying together our mission, vision and values.

The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people - because diversity of people and ideas remains integral to our excellence as a global civic institution.

Advert information