Clinical Research Fellow in Device-Mediated Immunomodulation

Location: Churchill Hospital, Old Road Campus and Botnar Research Centre

Contract type: Fixed term for 36 months

Hours: Full-time and in person working

About the role

We are looking for a specialist trainee in radiology, oncology or surgery to become directly involved with clinical and pre-clinical research in the field of device-mediated immunomodulation for cancer therapy and to further their development towards a career as an independent academic clinician.

You will be working under the direct supervision of Dr. Paul Lyon and Prof. Constantin Coussios on the development of tumour targeted cavitation-based therapies using Focused Ultrasound, including novel systemically administered stimulus-responsive particles, with the potential for immune system stimulation. You will be directly responsible for pre-clinical and clinical research aimed at achieving a clinical trial in ultrasound-mediated immunomodulation. There may also be the opportunity to become involved in other trials of ablative and non-ablative therapies and isolated hepatic perfusion.

About you

You will have a medical degree, have completed foundation training and will hold a national training number in radiology, oncology or surgery. You are expected to have had some clinical exposure to minimally and non-invasive ablative therapies and to have demonstrated an interest in interventional oncology or interventional radiology, as evidenced through previous pre-clinical and clinical research contributions in the form of peer-reviewed journal publications or conference presentations. Experience in clinical trial design and/or previous contribution to oncology or interventional radiology clinical trials would be highly desirable.

This full-time post is available immediately from 28^th April 2025 and is fixed-term for three years, with the expectation of in-person working.

Application Process

If you would like to discuss this role please contact Dr. Paul Lyon (paul.lyon@nds.ox.ac.uk)

Applications for this vacancy are to be made online. You will be required to upload a supporting statement, setting out how you meet the selection criteria, curriculum vitae and the names and contact details of two referees as part of your online application. Please quote reference NDSA959 on all correspondence.

Only applications received before noon Friday 11^th April 2025 can be considered.

Interviews will be held on the morning of Tuesday 22 April 2025.

Committed to equality and valuing diversity.

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