Research Associate in Cancer Immunology

Location: South Kensington Campus

About the role:

Are you passionate about advancing cancer immunotherapy? As a Research Associate in Cancer Immunology at the Ono Lab, you will play a pivotal role in uncovering new mechanisms of anti-tumour T cell responses. This position offers the opportunity to conduct ground-breaking research aimed at developing novel strategies for immunotherapy treatments using cutting-edge methods including the Timer-of-cell-kinetics-and-activity (Tocky) tools, which have been developed in the Ono lab.

What you would be doing:

• Explore and elucidate mechanisms within the immune system, focusing on T cells and their regulatory pathways in the context of cancer immunity.
• Employ our lab-developed Timer-of-cell-kinetics-and-activity (Tocky) method, leveraging the unique properties of the Fluorescent Timer protein to analyse T cell dynamics at the single-cell level.
• Conduct comprehensive studies using a range of in vivo and in vitro models to advance our understanding of T cell behaviour and its implications for cancer treatment.

What we are looking for:

• Extensive experience with cancer models, particularly those relevant to T cell studies, as well as in vivo models for non-cancer T cell biology studies essential to advancing cancer immunology.
• A strong background in molecular biology techniques, including proficiency in flow cytometric analysis to characterize T cell differentiation and behaviour.
• Proven expertise in managing transgenic mouse colonies, with a strong commitment to high standards of animal welfare.
• Demonstrated ability to work effectively within a collaborative research team environment and supervise undergraduate and postgraduate students, fostering their academic and professional growth.

What we can offer you:

The role will offer opportunities for investigating the immune system using state-of-art techniques while developing your knowledge and skills in cancer immunology and T cell biology through academic interactions within our team and across department and our cross-institutional collaborative team. Seminars and workshops are regularly held at Department and within the cross-institutional collaborative team. These will provide you the opportunities to be trained in:

• Opportunities to delve into immune system research using state-of-the-art techniques, significantly enhancing your expertise in cancer immunology and T cell biology.
• Engaging academic interactions both within our department and through our cross-institutional collaborative network, enriching your research and professional network.
• Regularly scheduled seminars and workshops within the Department and across the collaborative teams, designed to keep you at the cutting edge of your field.
• Comprehensive training in advanced methodologies and technologies specific to your role, fostering both your personal and professional development.
• The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.
• Grow your career: gain access to Imperial’s sector-leading dedicated career support for researchers as well as opportunities for promotion and progression.
• Sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).
• Be part of a diverse, inclusive and collaborative work culture with various staff networks and resources to support your personal and professional wellbeing.

Further Information

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant.

If you require any further details about the role, please contact:

Dr Masahiro Ono – m.ono@imperial.ac.uk

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