Research Associate

Job description:

Are you interested in working in a dynamic research environment within a Russell Group University?  An exciting opportunity has arisen for a post-doctoral research associate with experience in molecular biology and in-vivo/ex-vivo modelling of breast cancer and bone metastasis to contribute to a new research project focused on developing a novel gene targeted therapy for the prevention of breast cancer bone metastasis. This is Breast Cancer Now funded project builds on previous data from the, world renowned, Ottewell laboratory showing that the proinflammatory cytokine, IL-1B, is a key driver of bone metastasis. This new project is designed to determine the efficacy of genetically targeting IL-1B signalling in the bone as a method of preventing metastatic outgrowth through retaining tumour cells in a dormant state. In addition, this project will utilise RNAseq and digital special imaging to determine the molecular mechanisms by which inhibiting IL-1B signalling promotes tumour cell dormancy in the bone metastatic niche.

The project will be delivered through working closely with the principle and co-investigators, technical colleagues and a PhD student. This project comes with generous funding to enable attendances at national and international conferences and you have the opportunity to write abstracts and contribute to production of research and review articles.

This is a full-time role for 48-months, in the first instance with the intension of applying for further funding. Where appropriate we are supportive of hybrid working and we are committed to exploring flexible working opportunities which benefit the individual and University.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

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