Research Fellow (x2 posts)

About us

The Institute of Immunity and Transplantation at the Royal Free Hospital is part of the Division of Infection and Immunity in the UCL Faculty of Medical Sciences, which brings together UCL Medical School and five other Divisions spanning clinical and basic biomedicine. Scientists in the Institute conduct immunology and immunotherapeutic research. Our aim is to link our fundamental laboratory research with the specialised clinical interests of our hospital partners.

Prof. Benedict Seddon directs an interdisciplinary team, including molecular and cellular immunologists. Key research goals are to gain a greater understanding of how homeostasis and function of different T cell compartments is maintained throughout the life course. https://profiles.ucl.ac.uk/13815-benedict-seddon/about

About the role

Applications are invited for two MRC funded Post Doctoral Research Associate position in the UCL Institute of Immunity and Transplantation in a research team led by Professor Benedict Seddon. The posts are funded by a five year MRC programme grant entitled “Control of T cell immunity by TNFRSF induced IKK-dependent inflammatory signalling pathways”. The overall aim of the project is to understand how TNFRSF signalling controls cell death and differentiation pathways in developing and effector T cell populations during viral infection (see DOI 10.1016/j.immuni.2019.01.004, 10.1126/scisignal.abo4094, 10.1038/s41418-024-01383-6).

The current projects will use powerful mouse genetic tools and multi-omic approaches to define novel mechanisms by which TNFRSF signalling controls T cell fate and function during anti-viral immune responses. The post-holders will be expected to perform the highest quality research under the direction of the Principal Investigator, and to work effectively with other group members.

The positions are available until March 2027 in the first instance with options to extend.

About you

Applicants should have a PhD (or about to be awarded) in a relevant subject, and significant experience of working in a research laboratory. Experience of transcriptomic analysis and viral infection models in mice are also desirable. Excellent oral and written communication skills are essential, as is willingness and ability to be collegial and a team player.

The positions will suit motivated postdoctoral scientists who wish to develop their career and pursue opportunities for independent fellowships.

Informal enquiries should contact Dr Benedict Seddon  – benedict.seddon@ucl.ac.uk.

Please see the attached job description and person specification for full details. Please also read the attached Candidate Guidance document.

All applications must include a supporting statement telling us, using examples, how you meet the essential criteria listed in the job description. Applications without a supporting statement will be rejected.

If you have any queries about the role or application process, have any technical issues, or need reasonable adjustments or a more accessible format to apply for this job online, please contact the staffing team.

What we offer

As well as the exciting opportunities this role presents, we also offer some great benefits. Please visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.

Our commitment to Equality, Diversity and Inclusion

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

Customer advert reference: B02-08242

Advert information