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Postdoctoral Research Fellow

The University of Edinburgh - College of Medicine and Veterinary Medicine - Edinburgh Medical School - Deanery of Biomedical Sciences - Centre for Discovery Brain Sciences

Location: Edinburgh
Salary: £40,247 to £47,874 per annum (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 10th January 2025
Closes: 20th February 2025
Job Ref: 11859

Full time, 35 hours per week

Fixed term: 60 months

We seek a motivated postdoctoral researcher to conduct primary research into how neurons transport mRNA to distal sites and use these mRNAs as substrates for local protein synthesis during synaptic plasticity.

The opportunity:

A Wellcome Trust CDA funded postdoctoral position is available in the lab of Dr. Paul Donlin-Asp (www.donlin-asp-lab.com). This project aims to understand how neurons transport RNA and decide when/where they are translated into protein. This project will use a combination of imaging of mRNA and local protein synthesis to track where and when mRNAs are made available for local protein synthesis. We will couple these data with advanced proteomics to understand the regulatory network of proteins controlling how these mRNAs move and when they are read into protein. For more information, don't hesitate to contact Dr. Paul Donlin-Asp (pdonlin@ed.ac.uk).

Your skills and attributes for success:

  • Appropriate degree with relevant post-graduate research experience. Usually a PhD (or PhD near completion) in Neuroscience/Cellular Biology/Biochemistry or equivalent professional qualification and/or experience.
  • Previous first-author publications in a neuroscience/cell biology-related subject area.
  • Experience working with laboratory animals/ culturing of primary rodent neurons.
  • Experience with stereotaxic injections (mice).
  • Previous experience with fluorescence imaging and analysis.
  • Ability to communicate complex information clearly, orally, and in writing.
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