Research Fellow

About us

Biosciences is one of the world’s foremost centres for research and teaching in the biological sciences and one of the largest Divisions within UCL, undertaking a significant amount of research and teaching. The Division has a diverse portfolio addressing all areas of biology from protein interactions to cell function, organism development, genetics, population studies and the environment. Computational modelling approaches are frequently used alongside experimental research programmes and much of our research crosses traditional boundaries, including the relationship of biodiversity to the health of the planet. Activity is underpinned by high calibre science technology platforms and state of the art equipment. Educational activity includes a range of undergraduate programmes, an expanding number of Masters Programmes and a substantial number of postgraduate research students.

This is an exciting opportunity to join the RNAP laboratory at the Institute for Structural and Molecular Biology at UCL. Our research is focussed on the structure, function and evolution of gene expression in archaea. This research program is about the coupling of transcription and translation in Sulfolobus, and we are seeking three enthusiastic, knowledgable and hard-working individuals to push the frontiers of science!

About the role

The main purpose of this position is to carry out cutting edge research. The team for this project includes a biochemist, a structural biologist, and a systems biologists with experience in functional genomics. The three will work as closely knit team in a multidisciplinary fashion, taking ownership of their project and happy to collaborate.

Your research will include multiomics approaches applied to archaeal microorganisms including:

• Genome-wide occupancy mapping of transcription components (including ribosome profiling, ChIP-seq, NET-seq, ATAC-seq, KAS-seq etc.),
• Transcriptome (RNA-seq, SRS, LRS etc.) analyses
• Proteome/MS analyses
• Importantly, all the above includes both work at the bench and subsequent data analysis.

This role is an open-ended contract with a funding end date of 28/02/2030 in the first instance.

Research Fellows - 'Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Grade 6B (salary £34,502 - £36,348 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD Thesis.'

If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact Biosciences staffing at biosciences.staffing@ucl.ac.uk..

About you

You will need the following skills and experience: 1. Proven track record in genome-wide occupancy mapping, transcriptomics and proteomics 2. Successful candidates need experience in both lab work and data analyses 3. Preferably published in the fields of transcription or translation 4. You will be expected to produce independent and original research contributions 5. In addition to developing and conducting the research, you will communicate results as scientific papers and in scientific presentations at local, national, and international conferences.

Customer advert reference: B02-08080

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