Senior Technician - Research (Fixed term)

Applications are invited for a motivated laboratory research technician, whose expertise lies in molecular genetics techniques, to work with Ian Sayers and Simon Johnson on a UKRI CCRM funded project, entitled “Advanced Interdisciplinary Models of dEstructive lung Disease: AIMED”. The main aim of this programme of work is to use a multidisciplinary approach to advance our mechanistic understanding of destructive lung diseases such as chronic obstructive pulmonary disease (COPD) and lymphangioleiomyomatosis (LAM). The programme will use quantitative imaging, biological and clinical data of tissue injury and repair from LAM and COPD patient lungs alongside the development of mathematical and computational models to predict changes in lung structure and function. This is a collaboration between the Universities of Nottingham, Leicester and Birmingham. 

You will join a team, led by Professors Ian Sayers and Simon Johnson, whose main areas of research include understanding the molecular and cellular basis of respiratory disease. The team includes Professor Bindi Brook and Dr Reuben O’Dea, who develop mathematical and computational models linking cellular mechanisms with tissue level biomechanics, Dr Gowsh Poologundarampillai (University of Birmingham) who has expertise in high-resolution tissue imaging and Dr Himanshu Kaul (University of Leicester) whose expertise is in linking genetics with cellular behaviour via agent-based computational models. 

The project includes studying gene expression in lung tissue and the characterisation of cells and samples from patients with respiratory disease. The successful candidate will be expected to play a key role in the day-to-day running of a busy laboratory area. 

Candidates must have proven technical experience in relevant techniques and equipment, along with excellent communication skills and capability to organise own and other’s activities to meet set deadlines.  A strong background in primary cell culture, molecular biology and imaging would be an advantage, but training can be offered. The successful candidate will gain highly transferable skills including a range of techniques used in primary human cell biology, imaging and transcriptomics. 

This is a full time post (36.25 hours), and is available from 1st February 2025 or as soon as possible thereafter and will be offered on a fixed-term contract for 12 months. 

Requests for secondment from internal candidates may be considered on the basis that prior agreement has been sought from both your current line manager and the manager of your substantive post, if you are already undertaking a secondment role.

Informal enquiries may be addressed to Ian Sayers, email Ian.Sayers@nottingham.ac.uk. Please note that applications sent directly to this email address will not be accepted.

Advert information