Postdoctoral Research Scientist - Neuronal Cell Biologist

Contract & job type: Fixed-term, Full-time until 31 December 2026

About us:

At the Department of Physiology Anatomy & Genetics (DPAG) we undertake discovery science where we reassemble physiological processes at the molecular, cellular, tissue and systems level of organisation. In so doing we provide a bridge to translational medicine, and interface between physical and life sciences. We are committed not only to innovative research and the highest standard of teaching, but also to creating an inclusive and supportive working environment.

Overview of the role:

We are seeking a Postdoctoral Research Scientist - Neuronal Cell Biologist to join the Wade-Martins Laboratory at the Kavli Institute of Nanoscience Discovery within DPAG. The ideal candidate will have experience working in neuronal models of neurodegeneration, ideally in human stem cell-derived models, and a good knowledge of Parkinson’s disease. You will be responsible for differentiation of iPSC-dopamine neurons from Parkinson’s patients and controls and applying cellular and molecular techniques to probe endolysosomal and mitochondrial biology, including RNA-seq profiling, to validate a novel therapeutic target. This post is available from 1st January 2025 for two years.

Key responsibilities:

• Differentiate iPSC-dopamine neurons from Parkinson’s patients and controls, using cellular and molecular techniques to study endolysosomal and mitochondrial biology
• Perform RNA-seq profiling, manage research projects, contribute new ideas, and collaborate on scientific reports.
• Present research proposals and findings.

Selection criteria:

• Hold, or be close to completion of, a PhD/DPhil in molecular and cellular neuroscience
• Knowledge of Parkinson’s disease
• Experience in human pluripotent stem cell culture
• Expertise in cellular assays and molecular neuroscience techniques.

What we offer:

Your wellbeing at work matters, so we offer a range of family friendly and financial benefits including:

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle and electric car loan schemes
• Employee Assistance Programme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

While this is a full-time role, we welcome applications from individuals who wish to be considered for flexible working arrangements.

How to apply:

Please provide a supporting statement outlining how you meet the selection criteria along with your CV, and the details of two referees as part of your online application.

The closing date for applications is 12 noon on Tuesday 26th November 2024.

Interviews are likely to take place during the week commencing 9th December 2024 and may be face to face or held on Microsoft Teams.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford. 

Follow us:  

Stay connected with us on LinkedIn,  X and  Instagram to learn more about our work and culture.

Informal enquiries about the role may be directed to the DPAG HR Team: hr@dpag.ox.ac.uk

DPAG’s Statement of Inclusion:

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. Our policies, practices and  Respectful Behaviours Framework underpin this commitment.

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