Research Fellow in Cancer RNA Biology

About the role

A post-doctoral position is available in Dr. Leandro Castellano’s laboratory to investigate the role of non-coding RNA in pancreatic adenocarcinoma. The project will focus on how non-coding RNAs regulate tumour progression and metastasis, with the aim of identifying novel therapeutic targets.

Using CRISPR/Cas9 genome editing, RNA-immunoprecipitation, and RT-qPCR, the successful candidate will employ cutting-edge molecular techniques to modify cancer genomes and explore RNA-protein interactions. This project is part of an exciting collaboration with Prof. Florian Kern from the Brighton and Sussex Medical School, providing access to state-of-the-art facilities and a multidisciplinary research environment.

This role offers an excellent opportunity to contribute to impactful research in the growing field of RNA biology and its application in cancer therapeutics. The work has the potential to uncover new RNA-based interventions for pancreatic cancer, an area with urgent clinical need.

About you

Applicants should have a solid background in cancer biology, with a strong preference for expertise in pancreatic adenocarcinoma. Candidates should be proficient in growing cancer cells  and possess hands-on experience with CRISPR/Cas9 technology. Additionally, they should be prove experience in techniques for studying gene expression and RNA biology, such as RT-qPCR, RNA immunoprecipitation, and biochemical methods, including western blotting. The ideal candidate will demonstrate a comprehensive understanding of these advanced molecular biology techniques and be capable of applying them to investigate RNA-protein interactions and other critical aspects of cancer biology.

About our Division/School

Please find further information regarding the School of Life Sciences on our website.

The School of Life Sciences is proud to hold a Silver Athena Swann Award.

Why work here

Sussex is a renowned, multi-accredited, research-led International University and this is only possible because of the people that work here. Whether you are a member of Faculty, part of a Professional Services team or a Student, it’s our people that make us great and we want you to be part of that.

Find out more about our reward and benefits package.

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Further Key Information

Please contact Dr Leandro Castellano (L.Castellano@sussex.ac.uk) for informal enquiries.

For full details and how to apply, click the 'Apply' button above.

The University is committed to equality and valuing diversity, and applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in Science, Technology, Engineering, Medicine and Mathematics (STEMM) at Sussex.

The University of Sussex values the diversity of its staff and students, and we welcome applicants from all backgrounds.

The University requires that work undertaken for the University is performed in the UK. 

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