MRC Postdoctoral Research Scientist - Lymphocyte Development (3 Years)

A 3 year postdoctoral position is available at the MRC Laboratory of Medical Sciences (LMS) to work in the Lymphocyte Development group headed by Professor Matthias Merkenschlager. This position is expected to be filled by the successful candidate from December 2024. The LMS is a world-class research laboratory where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. Funded by the MRC as part of UK Research and Innovation, the LMS has a collaborative working culture and new state-of-the-art building based in the heart of West London in the Hammersmith Hospital Campus.

This project will focus X-linked competition, a newly discovered process by which X-chromosome sequence variation alters organismal development and skews the expression of X-linked sequence variants in a cell-type-specific manner (Buenaventura et al., 2024, Nature Genetics, published online 26th July, DOI 10.1038/s41588-024-01840-5). X-linked competition is unique to XX individuals and appears distinct from other known forms of cell competition that eliminate unfit cells from the developing organism

The successful candidate must hold a PhD or equivalent. Expertise in the biology of cohesin / CTCF and computational skills would be a substantial advantage. The successful candidate will have the ability to develop and apply new concepts, have a creative approach to problem solving, and will be able to write clearly and succinctly for publication.

This is an MRC Postdoctoral Scientist position providing training and development supporting postdoctoral scientists in early or changed career paths helping establish them as successful research scientists in their chosen field. The MRC is a unique working environment where our researchers are rewarded by world class innovation and collaboration opportunities that the MRC name brings.

We offer a wide range of employee benefits, including 30 days annual leave, a defined benefit pension scheme, family friendly policies, and support with CPD. For more details, visit benefits of working for UKRI.

We are committed to advancing EDI and as "Disability Confident" employers, we guarantee to interview all applicants with disabilities who meet the minimum criteria for the vacancy. Learn more about some of our workplace inclusion initiatives.

For full details of this post and to complete an online application, click on the ‘Apply’ button above and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job and your motivation). Please quote reference number LMS – 2479.

Applications which do not provide a cover letter will not be considered.

Closing date: 21 days

Final appointment will be subject to pre-employment screening

*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments.  The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.