Laboratory Research Scientist - Organ Morphodynamics Lab

Location: The Francis Crick Institute, Midland Road, London

Short summary

This position is for a fixed-term Laboratory Research Scientist (LRS) in the Organ Morphodynamics Laboratory led by Dr Rashmi Priya. The LRS will mainly contribute towards developing novel tools and technologies for the lab and will also run their independent project(s). The suitable candidate will be expected to collaborate with other members of the laboratory and support their ongoing projects. The specific details and aims of the project(s) will be developed in consultation with the supervisor and will also be driven by the candidate’s training and interest.

In our lab, we aim to unravel the underlying mechanical, molecular and geometric interactions that transform a developing heart from a simple epithelium into a highly intricate patterned organ. We are a highly interdisciplinary and collaborative laboratory. We combine the excellent tractability of zebrafish embryos with quantitative imaging, transcriptomics, biophysics, genetics, and predictive theoretical modelling to answer fundamental questions driving organ morphogenesis.

The role of a Laboratory Research Scientist in the Crick is diverse and rewarding with numerous training and development opportunities.

Key Responsibilities

These include but are not limited to:

• Contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and lead their own project(s).
• Developing and establishing new tools and techniques which includes generation and validation of zebrafish transgenic lines, HCR techniques, antibody characterisation.
• Providing experimental or technical support to other lab members.
• Contribution to proof-of-concept studies at the initial stages of different projects – which includes generation and validation of various tools (transgenic lines, mutants), imaging and image analysis.
• Willingness to actively contribute to a productive and positive lab atmosphere

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

• If you are interested in applying for this role, please apply via our website.
• The closing date for applications is 6/10/2024.
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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