Research Associate

The role

The research associate will be based in the Department of Translational Health Sciences within Queens’ Building of the Bristol Royal Infirmary hospital, a cross-disciplinary teaching, clinical and laboratory environment. 

The postholder will support work on a British Heart Foundation funded project entitled ‘Validation of novel LncRNAs with preventative roles in adverse cardiac fibrosis’ under Dr Sarah Smith’s supervision. The project involves the characterisation of the role of long non-coding RNAs in cardiac fibrosis using in-vitro and ex-vivo experimental models, molecular biology techniques, analysis of cell signalling pathways, protein analysis and cell behaviour assays. The post holder will be able to work independently and have the experience to facilitate high quality research with a translational science focus.
This role is fixed term until 28/02/2025. A blended and flexible working approach is possible including some sessions working from home. 

What will you be doing?

You will:

• Perform laboratory research, in particular cell culture, cell behaviour assays and live cell imaging, molecular and protein biology assays.
• Recording and analysing data and preparing summaries including statistical analysis, figure preparation, abstract, presentation and manuscript drafting.
• Trouble-shooting laboratory techniques.
• Work collaboratively with colleagues across the Bristol Medical School and the wider Bristol Heart Institute community to facilitate high-quality teaching.

Perform administrative duties as agreed with the line manager.

You should apply if:

• You have a PhD or working towards one (preferably in cardiovascular science).
• You have research experience and publication of research on cardiovascular disease.
• You have demonstrable experience of primary cell culture and analysis, including live cell imaging.
• You have experience of molecular and cellular cardiovascular biology.
• You are great at communicating research plans and results both in written and oral form.

Nice to have:

Previous experience in:

• Development of new laboratory methods.
• Experience in cardiovascular fibrosis.
• Knowledge of LncRNAs and MicroRNAs.

The Interview process is expected to be on Friday 26th July 2024

Additional information

Contract type: Fixed Term until 28/02/2025

Work pattern: Full-Time

School/Unit: Bristol Medical School

Shift pattern: 35 hours per week

For informal queries, please contact: Dr Sarah Smith; s.smith@bristol.ac.uk

This advert will close at 23:59 UK time on 11/07/2024

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