Post-doctoral Research Associate in RNA Therapeutics for the Treatment of Prostate Cancer

Job Summary:

We invite applications for a Post-Doctoral Research Associate position from outstanding, highly-motivated applicants with an interest in DNA damage and the use of RNA-based therapeutics for the treatment of prostate cancer.

You would be joining a dynamic and expanding group, undertaking collaborative and multidisciplinary work with the aim of progressing a novel DNA-damaging small RNA-based therapeutic towards clinical trials. This role provides a unique opportunity to assess therapeutic efficacy in both animal and patient-derived models. Research is conducted in collaboration with world-leading academic scientists from Imperial College London and chemists/biologists from the Nucleic Acid Therapeutics Accelerator, offering excellent opportunities to develop skills and networks.

Duties and responsibilities

You should be well-organised, self-motivated, able to work effectively as part of a team, and passionate about excelling in biomedical research. You will be required to pro-actively liaise with diverse teams, thus excellent communication and organisational skills are essential. You will also demonstrate a passion for developing new research capabilities.

Essential requirements

• You will hold a First Class or an Upper Second Class degree (or equivalent overseas qualification) and a PhD in molecular or cell biology, or a closely-related discipline.
• The successful candidate will hold a full ASPeL personal licence from a UK institution, or equivalent from non-UK institution.
• You will have published a minimum of one research paper as first author in a peer-reviewed publication and will demonstrate a deep and up-to-date understanding of RNA and cancer biology.
• In addition, you should evidence a broad portfolio of molecular and cell biology techniques. Preference will be given to candidates with experience in several of the following: tumour xenograft establishment and manipulation, in vivo drug delivery, culture of primary human tissues and cell lines, RNA manipulation/functional assays.
• Proficiency in bioinformatic analysis of RNA-seq and publicly-available omics data sets is advantageous, and knowledge of prostate cancer molecular biology is highly desirable.

You will also enjoy problem solving and be self-motivated, ambitious, disciplined and cooperative. There will be opportunities to acquire experience in supervision of research students and staff. The post is funded by Prostate Cancer Research and provides the opportunity to work within the Division of Cancer, Imperial College London, one of the leading research-led universities worldwide. This offers an outstanding environment for basic, clinical and translational research and a broad range of support and career development opportunities.

Further information

This is a Full Time and fixed term role until May 2026 based at the Hammersmith Campus

To apply online for this vacancy and to view further information about the role, please click on the Apply button above.

Further details of the project are available in the Job Description (LINK). For informal enquiries please contact Dr Claire Fletcher (claire.fletcher07@imperial.ac.uk) Information relating to the research interests of the group may be found at:

For technical issues when applying online please email sjobs@ic.ac.uk.

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