Research Assistant

“Neuronal cell biologist in stem cell-derived neuronal models of Parkinson’s disease”
Full-time, Fixed Term until 31 December 2025

Applications are invited for a Research Assistant neuronal cell biologist to work on a project to study stem cell-derived neuronal models of Parkinson’s disease. The project, funded by the Oxford/GSK Institute of Molecular and Computational Medicine, represents an exciting opportunity to undertake translational work at the interface between academic and industry research in an exceptional setting. This work will study cellular and organelle phenotypes to better understand the molecular mechanisms of disease in induced pluripotent stem cell (iPSC)-derived dopamine neurons and glia generated from Parkinson’s patients.

Duties will include undertaking laboratory experiments; interpretation of data; imaging analysis; differentiation and characterization of iPSC-derived neurons and glia through read-outs of organelle dysfunction in cellular models of Parkinson’s; preparation of data for publication; contribute to wider project planning and determine the most appropriate methodologies to test hypotheses. You will have excellent practical experience of working with neuronal or glial cell cultures and good knowledge of neurodegenerative disease. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.

Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.

The post is available from September 1st 2024 to 31st December 2025. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, Parks Road, Oxford, OX1 3QU.

Informal enquiries may be directed Professor Richard Wade-Martins (richard.wade-martins@dpag.ox.ac.uk).

Closing date for applications is midday on Thursday 11th July 2024. Shortlisted candidates will be invited for interviews, which are likely to be held two weeks after the closing date.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion

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