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Clinical Research Associate (Fellow)

Newcastle University - Medicine

Location: Newcastle upon Tyne
Salary: £41,634 to £70,425 per annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 21st March 2025
Closes: 18th April 2025
Job Ref: 28001

Company description:

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Job description:

The Role

We seek an enthusiastic and motivated doctor to work as a Clinical Research Associate (Fellow) on a major international project investigating the progression of cirrhosis. The ADVANCE study (Accelerating Discovery: ActioNable Cirrhosis Endpoints) is a multicentre clinical study investigating the factors that influence survival in cirrhosis caused by Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD, formerly called nonalcoholic fatty liver disease) and will help develop better diagnostic tests and identify new treatment targets.

The overall aim of the project is to understand how advanced MASLD progresses to cirrhosis and determine whether they are useful biomarkers for patient stratification, predicting disease course, hepatic decompensation and adverse outcomes in a well characterised, prospectively recruited patient cohort. The study will be important in the development of better diagnostics to monitor cirrhosis progression and to help identify new ways to treat cirrhosis. It would be the ideal focus for a higher degree.

This post provides a unique opportunity to develop a practical understanding of clinical research and develop your career. Working closely with a trial manager, you will be responsible for the day-to-day delivery of the ADVANCE study, under the supervision of Prof Quentin Anstee. You will liaise regularly with study sites to ensure good recruitment and communication. You will learn how to run clinical studies and work closely with scientists and clinical researchers. You will work with a variety of stakeholders including clinicians, laboratory scientists, industrial collaborators, statisticians, and patient groups. You will become involved in the delivery of clincial trials and may also have the opportunity to develop your own research project within the wider program.

Depending on your level of clinical training and experience, there may also be opportunities to gain further specialist hepatology training within the Freeman Hospital Liver Transplant Unit.

We are looking for a conscientious and self-motivated team player, with a thirst for new knowledge and an appetite for discovery. You will hold a medical degree and license to practice in the UK, and you will hold an up to date GCP certificate.

To apply for the position, we'll need your CV and a cover letter outlining how you are suitable for the role using evidence to highlight how you meet the essential criteria in the knowledge, skills and experience as listed in the job description.

This is a fixed term post initially for 12 months.

For further information please contact Professor Quentin Anstee Quentin.anstee@newcastle.ac.uk

Please note that if you are successful to this role, you will require medical clearance before you can commence in the role.

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