Senior Laboratory Research Scientist - High Throughput Perturbation Biology

Location: The Francis Crick Institute, Midland Road, London

About us…  

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role… 

In this role, you will develop, implement, and maintain laboratory operations and experimental techniques. Your responsibilities will include independently designing and establishing antibody-based assays, such as immunofluorescence, flow cytometry, and mass cytometry, and integrating them with automation infrastructure to create scalable and reproducible pipelines for quantifying the signalling responses of cell lines and organoids to perturbations with small molecule and growth factors. You will collaborate with team members to design and execute experiments, while also overseeing lab operations and providing training to other lab members.

What you will be doing… 

As an SLRS at the Crick, you will:  

• Introducing, maintaining and updating lab protocols and lab techniques.
• Designing and conducting experimental activities.
• Training of lab members in techniques.
• Involvement in day-to-day operation of the laboratory, including (but not limited to) maintenance of safety standards, restocking and purchasing, and general organisation.
• Continue professional development through maintaining awareness of developments in the wider research communities.
• Help to develop others by mentoring and sharing expertise and experience

About you

You will bring: 

• Proficiency in molecular assay development, optimization and validation
• Demonstrated ability to design, plan, and execute experiments independently.
• Hands-on experience in culturing and manipulating cell lines.
• A postgraduate qualification in a relevant subject or equivalent experience.
• Strong analytical skills to interpret experimental results and troubleshoot effectively.
• Proven ability to train and mentor team members in laboratory techniques and protocols. 

To see the complete job description, click here.

To see more about team/Group Leader click here 

About Working at the Crick… 

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact nicola.gyte@crick.ac.uk 

To read more about our EDI approach, click here.   

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

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