Research/Senior Research Associate

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Salary
Research Associate: £35,116 to £45,413 per annum.
Senior Research Associate: £46,735 to £55,755 per annum.

The Role
We are recruiting a Research Associate/Senior Research Associate to support the Transplantation and Regenerative Medicine laboratory working with Dr. Bill Scott, focusing on pancreas and islet research within the Newcastle University Translational and Clinical Research Institute. The post-holder will work across traditional industry/academic boundaries in close collaboration with industry and NHS partners within a dynamic multi-disciplinary team focused on rapid clinical translation.

This post will involve laboratory-based research, working with human donor tissue for primary cell isolations, tissue engineering, characterisation, and preservation studies with a focus on rapid clinical translation. This project will combine traditional lab skills, aseptic techniques, tissue and cell engineering methods to further understanding of pancreatic tissue and islet cell transplantation towards improving clinical care for those suffering severe Diabetes. This is being achieved by addressing core challenges in pancreatic islet transplantation. This project has the potential to enable a new clinical standard of care in human pancreatic islet transplantation.

Existing approaches to utilise islets of Langerhans for treatment of severe type-1 diabetes have been limited by nutritional restrictions during the peri-transplant period and subsequent loss of function prior to engraftment. This project will focus on process optimisation validation and documentation for clinical-translation of Kugelmeier's SP5D platform to standardise islet-spheroid size to treat type-1 diabetes, overcoming this key nutritional limitation. You will: 1) optimise cell-dissociation/re-aggregation from cadaveric isolated islets; 2) scale-up the process; 3) contribute to the generation regulatory-documentation for submission.

This post is fixed-term for a period of 12 months.

For informal enquiries contact: Dr Bill Scott (bill.scott3@newcastle.ac.uk)

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/.

Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/.

You will work closely with the project leadership team (Dr Bill Scott, Dr Ana Ferreira-Duarte), our industry partner (https://www.kugelmeiers.com/), Regulatory Bodies, other team members, and contribute to the management of the wider programme of work and support the planning and coordination of activities.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

For Research Associate, we are looking for an individual that has a PhD related to either transplantation or regenerative medicine.

For Senior Research Associate (SRA), we are looking for an individual that has a PhD in a relevant subject with several years of experience as a postdoctoral researcher. Having an impressive set of relevant published papers and ability to be involved in grant applications is essential.

We are especially interested in individuals with direct experience working in a regulated or healthcare environment as well as those experience working with.

Please note that if you are successful to this role, you will require medical clearance before you can commence in the role.

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