Senior Laboratory Research Scientist (SLRS)

Location: The Francis Crick Institute, Midland Road, London

Contract: 3 yr fixed term contract, Full time

About us…  

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role… 

The Gutierrez lab is in the research group “Host-pathogen interactions in tuberculosis” and has a long-standing interest in developing novel human induced pluripotent stem cell (iPSC)-based in vitro models of complex disease to study infection and treatment (Pellegrino et al.,2021; Aylan et al., 2023; Bussi et al., 2023). The SLRS position has been created to ensure the successful implementation of projects that aim to develop bioengineered stem cells based cellular systems to better understand lung infection and treatment. Specifically, we are engineering physiologically inspired human lung models combining human (iPSC) technologies with microfluidic devices. 

This role is critical to generate tools and perform cell-based experiments, requiring substantial experience in human induced pluripotent stem cell (iPSC) culture, differentiation and reprogramming. Experience in CRISPR/Cas9 genome editing is desirable. You will be part of a diverse and collegial team focused on advancing human iPSC-derived technologies to study infection and treatment. You will provide deep technical knowledge and hands-on expertise in the culture, characterization and differentiation of human iPSCs into lung cells.   

What you will be doing… 

As an SLRS at the Crick, you will:  

• iPSC culture and maintenance 
• iPSC differentiation and differentiated cell production  
• iPSC characterisation  
• Somatic cell reprogramming into iPSC  
• iPSC gene editing  

About you…   

You will bring…  

• Extensive experience in long-term iPSC culture, differentiation, and characterization (imaging and flow cytometry). 
• Ability to independently propose, design, execute and report on research projects, as well as to work collaboratively with an interdisciplinary research team. 
• Proven track record of scientific publications

To see the complete job description, click here. 

To see more about team/Group Leader here. 

About Working at the Crick… 

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact nicola.gyte@crick.ac.uk.

To read more about our EDI approach, click here.  

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

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