Research Fellow

About us

The mission of the UCL GOS Institute of Child Health is to maximise and advocate for the holistic health of all children, young people and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. The 2024-29 GOS ICH strategy focuses on its five scientific programmes. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-class education an d training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.

About the role

Applications are invited for a motivated Research Fellow to take part in a research project aimed at designing antisense oligonucleotides (AONs)-based therapies to improve disease severity in LAMA2-related congenital muscular dystrophy (LAMA2-RD). The post holder will be involved in the characterization of molecular mechanisms altered in patient-derived cells and the design of AONs target to a genomic region controlling perturbed processes in the disease. Animal studies will be also performed in collaboration with San Raffaele Hospital (Milan) to validate human findings. This post is available for 24 months in the first instance on £43,124 pa.

About you

The successful candidate will have a PhD in Molecular or Cell Biology, with a strong interest in translational neuroscience. You will have experience in cell biology and basic molecular techniques including RNA and protein isolation from cells, quantitative RT-PCR, and Western Blot. You will be dedicated to teamwork and able to meet deadlines as set with the Principal Investigator and international collaborators. 

Customer advert reference: B02-08348

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