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Research Associate (Theoretical Physics)

University of Sheffield - Faculty of Health

Location: Sheffield
Salary: £37,999
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 18th February 2025
Closes: 18th March 2025
Job Ref: 830

Job description:

We are seeking a theoretical physics/applied mathematics/computational biology post-doctoral research associate to join our multidisciplinary team studying how the immune system controls infection. Cryptococcal meningitis (CM) is a fungal infection of immunocompromised individuals, responsible for over 100,000 deaths globally each year and 20% of AIDS-related deaths. In this project, we are studying a new way that macrophage immune cells can ingest and kill Cryptococcus. We have discovered that macrophages have sub-micron ridges on their surface which improves their ability to interact and phagocytose Cryptococcus.

Key Responsibilities

  • Use analytical and computation methods to understand the biophysics of host pathogen interactions in human infections.
  • Work as part of a multidisciplinary team across human infection, in vivo and cell models, analytical and computational theoretical models.
  • Analyse data and interpret results to contribute to the understanding of immune responses to Cryptococcus.
  • Collaborate with fellow researchers and team members to successfully implement research projects.
  • Prepare manuscripts, reports, and presentations to communicate findings to the scientific community.
  • Mentor and support junior members of the research team.

What We Offer

Our team at the University of Sheffield, is committed to encouraging an inclusive and accessible research environment. As a member of our team, you will have access to advanced facilities and resources to support your research. We are dedicated to your professional growth and will provide opportunities for career development and mentorship. You will be part of a passionate team that strives to understand and combat human infections through pioneering research.

Join us in our mission to make a significant impact on global health. Your work will contribute to advancing our understanding of immune system interactions and potentially lead to new therapeutic approaches for treating cryptococcal meningitis and other infections.

We are an equal opportunity employer and value diversity at our company. We do not discriminate based on race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodations.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

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