Senior Laboratory Research Scientist

Location: The Francis Crick Institute, Midland Road, London

Contract: 1-year Fixed term, Full time

About us…  

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. 

To learn more about the Crick, click here.

About the role… 

We are looking for an enthusiastic and highly motivated researcher with strong expertise in cell biology interested in developing novel more sensitive screening approaches for molecular glue identification to accelerate drug discovery in the targeted protein degradation field. The Schreiber lab is part of the Prosperity Partnership between the Francis Crick Institute, AstraZeneca and Imperial College London which is focused on developing a rule book for the rational discovery of molecular glue degraders.  We are studying how autophagy and the ubiquitin proteasome system can be utilized to target a wide range of currently undruggable disease relevant targets (e.g. protein aggregates and damaged mitochondria). The ultimate aim is to unlock novel biology and exploit its revolutionary therapeutic potential. 

Dependant on funding, there is potential for this role to be extended after the initial contract term. 

What you will be doing… 

As an SLRS at the Crick, you will: 

• Develop and lead your own projects 
• Contribute to other projects within the lab on a collaborative basis 
• Provide organisational and administrative expertise for this multi-disciplinary lab  

About you…   

You will bring…  

• PhD in molecular and/or cellular biology, biochemistry, biophysics or related disciplines, or in the final stages of PhD submission.
• Strong expertise in mammalian cell culture 
• Experience in developing quantitative high-throughput screening approaches in cells
• Expertise in studying protein interactions preferably in cells
• Excellent organisational skills, thorough record-keeping and attention to detail
• Good communication, presentation, and data analysis skills

To see the complete job description click here. 

To see more about team/Group Leader click here. 

About Working at the Crick… 

Our values  

• We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. 
• We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. 
• We are collegial. We show respect for one another, work cooperatively and support the wider community. 

At the Crick, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. If you need assistance with your application, please contact nicola.gyte@crick.acuk.

To read more about our EDI approach, click here.  

What will you receive?  

We value our team members and are proud to offer an extensive range of benefits to support their well-being and development. You can find out more about what we offer here.

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