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Postdoctoral Research Fellow

The University of Edinburgh - CMVM - Institute for Regeneration and Repair - Centre for Inflammation Research

Location: Edinburgh
Salary: £40,247 to £47,874 per annum (Grade 7)
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 6th February 2025
Closes: 20th February 2025
Job Ref: 12023

Full-time: 35 hours per week

Fixed Term: 2 years

We are looking for a driven and enthusiastic Quantitative Geneticist Research Fellow to help deliver a large-scale single cell molecular QTL discovery programme supported by £5M of UKRI funding as part of the Edinburgh Molecular Mechanisms Cluster. 

This post is advertised as full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.  We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working.  

The Opportunity:

We have shown that molecular quantitative trait loci (molQTL) can reveal specific molecular mediators, cell types and states underlying disease, and lead directly to new, effective therapies. The Molecular Mechanisms Cluster (MMC) will systematically study single cells from primary human tissues, across a range of perturbation states, to reveal the molecular con- sequences of disease-associated genetic variation. This cross-cutting project combines precise laboratory techniques with advanced computational modelling.

This post will be based at the Baillie Gifford Pandemic Science Hub (PSH: psh.ac.uk) at the Institute for Regeneration and Repair. 

Your skills and attributes for success: 

  • A PhD (or near completion) or equivalent professional qualification and/or experience in the field of genetics, bioinformatics, computational biology
  • Strong expertise in performing eQTL analyses and/or integrating large-scale genetic and transcriptomic datasets (e.g., GWAS, RNA-seq)
  • Proficiency in programming languages such as R or Python and experience with bioinformatics tools
  • Strong planning and organising skills
  • Excellent written and verbal communication skills with ability to build rapport with colleagues and collaborators.
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