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Senior Bioinformatican

University of Oxford - NDM Experimental Medicine, John Radcliffe Hospital

Location: Oxford
Salary: £48,235 to £57,255 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year (pro rata).
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 28th January 2025
Closes: 12th February 2025
Job Ref: 177847

About the Role

We are seeking a creative and enthusiastic post-doc to lead on the design, conduct, supervision and publication of bioinformatic analyses in the Modernising Medical Microbiology (MMM) Unit (https://www.expmedndm.ox.ac.uk/mmm ). The Unit comprises approximately 40 researchers situated in Oxford, predominantly at the John Radcliffe Hospital. The group is taking a lead in infectious diseases research in the UK.
 
The MMM Unit undertakes large-scale epidemiological studies and pathogen sequencing, using a diverse range of sequencing technologies, including short-read (Illumina) and long-read (Nanopore) approaches. Team members have developed, and are iteratively improving, high-throughput methods for processing and analysing thousands of pathogen genomes. The aim is for the postholder to create computational workflows for sequence data analysis. This involves validation of these workflows which requires well-characterised genomes, referred to as “truth sets”. To create these, there needs to be close co-operation between the postholder and the lab team. Another key aspect of the work will be to work with the team to prepare bioinformatics pipelines to establish better computational prediction of antimicrobial resistance.
 
The University of Oxford is partnering with the Ellison Institute of Technology (EIT) to further develop Pathogen Analysis Services in order to establish a world-leading enterprise delivering global pathogen sequence analysis for both public health and patient care diagnostics for all major pathogens. This is an exciting role, with the opportunity to work in an interdisciplinary team, alongside other bioinformaticians. The wider team includes clinicians, research software engineers and bioinformatics and biostatistics support, and the goal is to validate the sequencing analysis and microbiological services.  It has strong collaborative links to the UK Health Security Agency (formerly Public Health England), European Bioinformatics Institute, and the Global Health Security Consortium formed by the Tony Blair Institute, Larry Ellison Foundation and University of Oxford.
 
About You
 
The post-holder will need a track record of developing and delivering their own bioinformatic analyses through to peer-reviewed publication, as well as a range of bioinformatic experience in programming languages and systems relevant to academic research.
 
You should hold a PhD (or equivalent) in a relevant scientific subject
 
Applications from those returning to work after career or other breaks would be welcomed.
 
About the Nuffield Department of Clinical Medicine
 
What We Offer
 
As an employer, we genuinely care about our employees’ well-being and this is reflected in the range of benefits that we offer including:
 
•         Flexible working
•         An excellent contributory pension scheme
•         38 days’ annual leave (including bank holidays)
•         A comprehensive range of childcare services
•         Family leave schemes
•         Cycle loan scheme
•         Discounted bus travel and Season Ticket travel loans
 
The University also runs a large number of social groups and sports clubs for those looking for more than just a great place to work.
 
Application Process
 
The post is full time and fixed term up to 31/03/2027.  Part-time working will be considered (0.8 FTE, 30 hours per week minimum).
Applications are to be made online. You will be required to upload a supporting statement and CV as part of your online application. Please include in your supporting statement why this is the right opportunity for you.
Only applications received before 12.00 midday on 12 February 2025 will be considered.
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