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Postdoctoral Research Scientist in Structural Biology: Antibodies and Glycoproteins

University of Oxford - Division of Structural Biology, Nuffield Department of Medicine

Location: Oxford
Salary: £38,674 to £43,171 p.a.
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 27th January 2025
Closes: 10th February 2025
Job Ref: 177857

Location: Division of Structural Biology, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN

Salary: Research Grade 7: salary in range £38,674 - £43,171 p.a. This is inclusive of a pensionable Oxford University Weighting of £1,500 per year.  

We are seeking to appoint a highly-motivated Postdoctoral Research Scientist to join Professor Bowden’s group to work in the area of integrated X-ray and EM-based studies of viral glycoprotein-antibody interactions. You will join a very lively and motivated international and interdisciplinary group of scientists at the Division of Structural Biology, Nuffield Department of Medicine. 

You will be responsible for managing your own academic research activities, adapting existing and develop new scientific techniques and experimental protocols, as well as testing hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate. You will also contribute ideas for new research projects and to the presentation of scientific results through journal articles, posters and oral presentations at national/international conferences. You will use specialist scientific equipment in a laboratory environment and represent the research group at external meetings/seminars. 

It is essential that you hold a PhD/DPhil (or close to completion) in a relevant subject (e.g. Structural Biology, Biophysics, Biochemistry, Virology) and have research experience in production and purification of protein samples for structure/function studies using mammalian and insect cell-based expression systems. You will have research experience in X-ray crystallography and/or cryoEM/cryoET, preferably of glycoproteins and membrane proteins and in biophysical and cell-based assays. You will also have documented evidence of work at the level expected of first author publication in a leading refereed journal as well as ability to manage the day-to-day running of a research project including assisting the work of junior researchers. Good communication skills, including the ability to present work at international symposia and to non-specialist audiences is essential for this role. 

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. 

This position is offered full time on a fixed term contract until 31 January 2028 and is funded by CEPI. 

Only applications received before 12 midday on 10 February 2025 will be considered. Please quote 177857 on all correspondence.

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