Research Associate

We have an exciting opportunity in the internationally renowned Sheffield Institute for Translational Neuroscience (SITraN) for a highly motivated Postdoctoral Researcher looking to use their skills in cell biology, gene editing and bioinformatics to explore the link between strenuous physical activity and the development of motor neuron disease. Working in the lab of Professor Dame Pamela Shaw you will be part of a larger interdisciplinary, translational project with the labs of Dr Ryan West and Dr Johnathan Cooper-knock. Based in SITraN you will have the opportunity to work in a vibrant research environment bringing together “basic” and clinical researchers at the forefront of MND and neurodegenerative disease research.

This project will build on our recent findings demonstrating Physical exercise is a risk factor for MND. In SITraN we have established patient-derived cell models of MND including disease-specific phenotypes such as TDP-43 pathology. You will use these models to interrogate the gene-environment interaction leading to exercise-induced MND. You will work closely with other team members developing a Drosophila model of the same process.

You will be expected to work independently, designing, executing, and evaluating experiments, under guidance of the principal investigators. You are also expected to contribute to the preparation of scientific manuscripts, attend and deliver seminars and supervise graduate students. You should have a PhD (or equivalent experience) in molecular or cellular biology, and/or neuroscience.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

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