Research Associate Fibrosis Research

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

The Role
The purpose of research in the Newcastle Fibrosis Research Group (NFRG) is to understand the biological processes that lead to the progression of age-related chronic diseases to loss of organ function and/or cancer. By developing a deeper understanding of processes such as inflammation, cellular senescence, fibrosis and tumour development we aim to unlock new drug targets and biomarkers that provide solutions to diseases that are highly prevalent in populations. We also aim to be continually advancing technologies such that the discoveries we make provide a higher level of detail of biological information and from experimental disease models that have relevance to human disease.

You will join a Pfizer funded project within the Newcastle Fibrosis Research Group under the direct supervision of Dr Lee Borthwick with significant oversight from Prof Andrew Fisher.

You will be responsible for delivery of experimental work to advance the Pfizer- Newcastle Pathogenic Tissue Target Mapping collaboration that aims to use spatial transcriptomics and proteomics to identify and validate novel therapeutic targets in chronic lung diseases including Idiopathic Pulmonary Fibrosis (IPF) and Chronic Obstructive Pulmonary Fibrosis (COPD). The project will involve tissue cultures (ex-vivo slice cultures and primary cells) as well as histological, biochemical and molecular approaches.

You will be responsible for collection, processing, analysis, presentation (writing, graph production, image production and oral presentations at national/international conferences) and storage of experimental data in accurate, secure, detailed and up- to-date records of all work carried out to GLP standard.

This post is fixed-term for a period of 12 month with a possibility to extend.

For informal enquiries contact: lee.borthwick@ncl.ac.uk.

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/.

Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

Please note that if you are successful to this role, you will require a Research Passport and a medical clearance before you can commence in the role.

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