Postdoctoral Research Assistant in Chemical/Cell Biology and Antimicrobial Resistance

Applications are invited for a Postdoctoral Research Associate to join a research team developing new approaches to combat antimicrobial resistance, working under the supervision of Dr Thomas Lanyon-Hogg for a period of 24 months. This project is funded by the Ineos Oxford Institute for antimicrobial research (IOI) and will be carried out in the Department of Pharmacology, the Centre for Medicines Discovery (CMD), the Sir William Dunn School of Pathology, and the IOI, all based at the University of Oxford.

This is an exciting opportunity to work with world-leading researchers and contribute to the development of innovative new approaches to combat antimicrobial resistance, which is a significant area of unmet medical need globally. Find out more about the Lanyon-Hogg group’s research at: Lanyon-Hogg group

Reporting to Dr Thomas Lanyon-Hogg, you will be a member of a research group with responsibility for conducting a research project to identify new molecules to combat antimicrobial resistance. You will have a discrete role as part of a collaborative and interdisciplinary research team based between the Department of Pharmacology, CMD, Dunn School of Pathology and the IOI. You will be responsible for establishing and conducting biochemical, cellular and chemical biology assays to identify and validate small-molecule ligands. You will be responsible for designing and conducting experiments, analysing data, communicating findings with the wider project team, preparing publications, and presenting results at conferences. You will also contribute to management of the TLH laboratory and provide guidance to junior members of the research group, including PhD and project students.

The appointee will be expected to manage their own academic research and administrative activities with a high degree of autonomy and independence, as the project will require work in multiple collaborating departments. This will involve small-scale project management to co-ordinate multiple aspects of work for presentations, publications, and patents. The appointee will analyse scientific data from a variety of sources to develop the project, reviewing and refining working hypothesis as required.

You should have  experience in biochemistry, microbiology, and/or chemical biology, inhibitor screening and drug discovery, and protein construct design and cloning. You must hold (or be close to completion prior to taking up appointment) a relevant PhD/DPhil in biochemistry, microbiology, cell biology, or chemical biology, together with relevant experience. Prior experience in  antibiotic drug discovery, assay automation and peptide synthesis would be an advantage.

The post is available from mid-February 2025. The University of Oxford and the Department of Pharmacology are Silver Athena SWAN award holders. Applications are particularly welcome from candidates in demographic groups that are under-represented in scientific research. Candidates will be assessed solely on scientific merit, and all applications will be anonymised before shortlisting.

The post is offered on a fixed-term basis for 24 months, funded by the Ineos Oxford Institute (IOI). The closing date for applications is Monday 13 January 2025.

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