Postdoctoral Research Associate in Structural Biology

About the role

We are seeking to appoint a Postdoctoral Research Associate to join the team of Prof. Elena Seiradake. The Seiradake group specialises in structural biology, cell biology and neurobiology, providing access to expertise and training in these areas. This role will focus on the functions of brain receptors in nervous system development. The work will involve some or all of the following methods: single particle cryo-electron microscopy, cryo-electron tomography, X-ray crystallography, surface plasmon resonance, protein engineering, mammalian cell culture, fluorescence microscopy, immunostaining.

This full-time fixed-term post is funded by the European Research Council for up to 3 years in the first instance.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

What We Offer

Your happiness and wellbeing at work matters to us, so we offer a range of family friendly and financial benefits including:

• An excellent contributory pension scheme
• 38 days annual leave
• A comprehensive range of childcare services
• Family leave schemes
• Cycle loan scheme
• Membership to a variety of social and sports clubs
• Discounted bus travel and Season Ticket travel loans

The University also runs an enormous amount of social groups and sports clubs for those looking for more than just a great place to work.

About you

You should hold a PhD/DPhil, or be near completion of a PhD/DPhil, in a subject area involving structural biology, and have excellent relevant skills in recombinant protein expression and purification using yeast, bacterial and HEK293 cell cultures. Experience in the purification of membrane proteins and mammalian cell cultures is essential, as well as using synthetic polymers, membrane scaffold proteins and saposin A and nanodisc technology. Experience in heavy metal transporter protein purification is expected as well as having experience in cell biology assays involving iPSC-derived cultures and cell lines using immunostaining and confocal fluorescence microscopy. You will also have experience in negative stain electron microscopy and sample preparation for single particle cryogenic electron microscopy. Strong experience using ATPase activity assays is also essential. You should be well-trained, enthusiastic and self-motivated, with excellent team-working and interpersonal skills. You should also have excellent communication skills. You may be required to travel overseas to conduct collaborative experiments as and when necessary to advance the research project

Application Process

Applications for this vacancy are to be made online via www.recruit.ox.ac.uk and Vacancy ID 176497. You will be required to upload your curriculum vitae and a supporting statement, setting out how you meet the selection criteria for the post, using examples of your skills and experience. As part of your application, you will be asked to provide details of two referees and indicate whether we can contact them now.

For further details, please click the 'Apply' button above.  Any further enquires may be directed to recruitment@bioch.ox.ac.uk.

The closing date for applications is 12.00 noon on Monday 25th November 2024. Only applications received before this time can be considered. Interviews for shortlisted candidates to be held on as soon as possible thereafter.

Committed to equality and valuing diversity

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