Research Associate / Research Assistant - Single Cell Genomics

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

Salary
Research Assistant: £32,296 to £33,882 per annum.
Research Associate: £34,866 to £45,163 per annum.

The Role
Have you got a passion for single cell genomics? Are you interested in joining a vibrant multi-disciplinary team working to understand in how mitochondrial DNA mutations affect cellular function?

We are looking for a motivated Post-Doctoral Research Assistant / Associate to join our team, backed by significant funding from a recently awarded Wellcome Career Development Award. This is an exciting opportunity to be part of a team at forefront of pioneering research from the very start of a project. Our goal is to determine how the nuclear and mitochondrial genomes interact in mitochondrial DNA disease. You will harness the power of large-scale, single-cell genomics to understand the cellular response to different levels of mitochondrial DNA mutations across different tissues, with a focus on immune cell function.

We are seeking candidates with a PhD or equivalent experience in single cell genomics and mitochondrial DNA disease or related areas. In this role, you will be based at our Newcastle Upon Tyne campus, which has fantastic transport links and state of the art facilities. You will join the world-class, multidisciplinary Newcastle Mitochondrial Research Group, renowned for our extensive experience in characterising mitochondrial function in both health and disease. The group also includes a vibrant Young Scientists Group. Our researchers work in close collaboration with NHS clinical activities, bridging basic and translational science to advance the understanding of mitochondrial biology to develop new therapies for patients and families.

The position is a full-time, fixed-term post for a period of 12 months in the first instance, starting as soon as possible. We recognise and support diverse personal circumstances and are open to discuss flexible working arrangements.

To apply for the position, we'll need your CV and a personal statement outlining how you are suitable for the role using evidence to highlight how you meet the essential criteria in the knowledge, skills and experience as listed in the job description.

Please focus your cover letter on the following key areas, outlining your ability and/or experience with:

• Designing and performing wet lab experiments to produce single cell genomic data, including experience of flow cytometry.
• Data analysis of single cell genomic datasets.
• Experience of culturing, stimulating and assessing the function of T cells.
• Collaborating regularly with the Principal Investigator, team members, and external partners to ensure high-quality research and the timely achievement of project goals.

If you have any questions prior to applying, please contact Dr Sarah Pickett (sarah.pickett@ncl.ac.uk).

Find out more about the Faculty of Medical Sciences here: https://www.ncl.ac.uk/medical-sciences/
Find out more about our Research Institutes here: https://www.ncl.ac.uk/medical-sciences/research/institutes/

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

Please note that if you are successful to this role, you will require medical clearance before you can commence in the role.

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