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PhD Studentship: Translational Control During Host-pathogen Interaction

University of Cambridge - Department of Pathology, Central Cambridge

Qualification Type: PhD
Location: Cambridge
Funding for: UK Students
Funding amount: Stipend at the current Research Council rate and University Fees.
Hours: Full Time
Placed On: 11th November 2024
Closes: 3rd January 2025
Reference: PK43848

Applications are invited for a fully-funded 4-year PhD studentship based in the Department of Pathology at the University of Cambridge under the supervision of Dr Betty Chung (https://www.path.cam.ac.uk/directory/betty-chung) starting October 2025.

Biotic stresses often unfold rapidly, demanding swift responses from both host and pathogen to ensure survival. Upon their encounter, a sophisticated network of gene regulation is instantly activated in both organisms, spanning transcription, translation, and protein turnover. While transcriptional regulation offers versatility, translational control enables potent, efficient and rapid adjustment in protein abundance, which is crucial during the initial stages of infection for both host and pathogen. This project seeks to unravel the intricate translational regulatory mechanisms governing host-pathogen interactions, aiming to decode the molecular dynamics and triggers that influence virulence, pathogenicity, and innate immunity. 

For a more detailed description of the project and application, please click on the 'Apply' button above. 

Applicants should hold (or expect to obtain) the equivalent of a UK 2.1 or higher in an undergraduate honours or Masters degree in a relevant subject. The studentship is open to those eligible for the Home rate of University fees.

Applications should include academic transcripts, CV, statement of purpose and 2 references. Please also explain your motivation why you wish to pursue a PhD in this area, outline your research interests and background, and describe the qualities and experience you will bring to the role. 

Funding notes: Funding* will cover the student's stipend at the current Research Council rate and University Fees. The studentship will be funded for four years from October 2025. *The studentship is only available to students who qualify for UK Home fees 

Please quote reference PK43848 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Closing date: 03 January 2025

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