Research Technician in Cancer Biology and Gut Health

About the role:

The Barry lab in the Department of Metabolism, Digestion and Reproduction is seeking to appoint a Research Technician in Cancer Biology and Gut Health to support a UKRI-funded project focused on studying active hydrolases and hydrolase regulators in colorectal cancer using ‘omics’ and advanced gut-culture models. The successful candidate will play a pivotal role in supporting the Principal Investigator and collaborating closely with clinical and fundamental science researchers within the Barry team and partnering laboratories. The post will have a varied role with wet laboratory, research, administration and compliance aspects.

What you would be doing:

You will support the day-to-day running of the Barry laboratory, assist with training/supervision of students and staff and carry out wet laboratory experiments including standard molecular biology techniques, protein assays (western analysis, enzyme kinetics and proteomics) and organoid culture. You will be responsible for laboratory support, including stock and consumable maintenance, laboratory compliance, and ensuring safety procedures are in place. You will be part of a thriving group of interdisciplinary researchers and students, and benefit from access and training from specialist facilities including the the NIHR Imperial BRC organoid facility.

What we are looking for:

• Bachelor's degree or equivalent in Life Sciences, Biochemistry, or a closely related field
• Proven experience of working in a laboratory in an institute of higher education or research institute
• Genuine interest in cancer biology and gut health
• Hands-on experience in molecular biology techniques, protein assays (e.g., western blotting, enzyme kinetics and proteomics) and cell culture (ideally organoid culture)
• Strong record-keeping skills for maintaining accurate lab notebooks, protocols, and results
• Experience in laboratory organisation/management
• A pro-active approach to health and safety, data management and research ethics
• Self-motivated and enthusiastic individual
• Able to work collaboratively to build and sustain working relationships
• Willingness to learn and implement new procedures and processes

What we can offer you:

• You will be part of an interdisciplinary team undertaking research which spans the boundaries of fundamental and clinical research
• The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity
• Dedicated training and development opportunities
• Full-time, fixed term post for 12 months
• Benefit from sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes)
• Be part of a diverse, inclusive, and collaborative work culture with various staff networks and resources designed to support your personal and professional wellbeing.

Further Information

Expected start date: January 2025

To learn more about the Barry research group, please visit the following link: www.imperial.ac.uk/metabolism-digestion-reproduction/research/digestive-diseases/nutrition-research/hydrolytic-enzymes-colon-inflammation-and-gastrointestinal-diseases-

If you require any further details on the role please contact: Dr Rachael Barry– r.barry@imperial.ac.uk

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