Back to search results

Higher Scientific Officer - Drug Metabolism and Pharmacokinetics

The Institute of Cancer Research - Clinical Pharmacology & Trials

Location: Sutton
Salary: £37,050 to £39,000 Per Annum
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 8th November 2024
Closes: 22nd November 2024
Job Ref: 1061

We are seeking to appoint a Higher Scientific Officer to join the Drug Metabolism and Pharmacokinetics (DMPK) team to support pre-clinical drug discovery projects. 

The key role is to support pre-clinical drug discovery projects. The post holder will work with other members of the team to evaluate the pharmacokinetics and metabolism of potential new anticancer drugs. The post holder will develop, validate, run and report in-vitro DMPK assays and perform in-vivo bioanalysis in line with Good Clinical Practice (GCP) guidelines to measure compounds of various modalities and identify metabolites in preclinical samples. The role involves extensive use of Liquid Chromatography-Mass Spectrometry (LC-MS) methodology. The post holder will also interpret analytical data using PK software to calculate pharmacokinetic parameters. Additionally, the candidate will be required to collate, interpret data and report results to both internal project teams and external collaborators. 

Key Requirements 

The successful candidate must have a BSc in Pharmacology/Toxicology, Analytical Chemistry or related subject. Laboratory experience preferably analytical, DMPK or similar is essential. We are looking to appoint an enthusiastic applicant to work in an interdisciplinary environment towards the goal of developing improved cancer therapeutics. The successful candidate will have the ability to work effectively and efficiently, both independently and as part of a team, where good communication is key, maintaining attention to detail and keeping appropriate records. The ability to work within the guidelines of Data Protection and Good Clinical Practice is essential. Knowledge of pharmacokinetics, in-vitro DMPK assays and drug development is desirable but not essential. 

Department/Directorate Information 

The post holder will be based in the Drug Metabolism and Pharmacokinetics (DMPK) team within the Centre for Cancer Drug Discovery (CCDD), part of the Division of Cancer Therapeutics. The centre is a multidisciplinary 'bench to bedside' centre, comprising around 200 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. The Centre for Cancer Drug Discovery’s exciting goal is to discover high quality drug candidates for validated biological targets and to progress these candidates to clinical trial. All the scientific disciplines are in place to make this possible. Our world-class biologists, chemists and drug metabolism specialists work together focusing on new molecular targets emerging from human genome and ground-breaking cell biology research. This is an exciting and fast-moving cancer research setup and offers the opportunity to work within a multi-disciplinary environment using state-of-the-art techniques and equipment. 

We encourage all applicants to access the job pack attached for more detailed information regarding this role. For an informal discussion regarding the role, please contact Ruth Ruddle or Angela Hayes via Email on ruth.ruddle@icr.ac.uk or angela.hayes@icr.ac.uk. 

Due to the high volumes of applications we receive, we reserve the right to close the advert before the published closing date once we have received a sufficient number of applications. Therefore, we advise that you to submit your application, as early as possible to avoid disappointment. 

Why work for us?

As a member of staff, you'll have exclusive access to a range of staff benefits.

The Institute of Cancer Research, London, is one of the world's most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. Further information about working at the ICR can be found on our website.

We value your feedback on the quality of our adverts. If you have a comment to make about the overall quality of this advert, or its categorisation then please send us your feedback
Advert information

Type / Role:

Subject Area(s):

Location(s):

Job tools
 

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Ok Ok

PhD Alert Created

Job Alert Created

Your PhD alert has been successfully created for this search.

Your job alert has been successfully created for this search.

Manage your job alerts Manage your job alerts

Account Verification Missing

In order to create multiple job alerts, you must first verify your email address to complete your account creation

Request verification email Request verification email

jobs.ac.uk Account Required

In order to create multiple alerts, you must create a jobs.ac.uk jobseeker account

Create Account Create Account

Alert Creation Failed

Unfortunately, your account is currently blocked. Please login to unblock your account.

Email Address Blocked

We received a delivery failure message when attempting to send you an email and therefore your email address has been blocked. You will not receive job alerts until your email address is unblocked. To do so, please choose from one of the two options below.

Max Alerts Reached

A maximum of 5 Job Alerts can be created against your account. Please remove an existing alert in order to create this new Job Alert

Manage your job alerts Manage your job alerts

Creation Failed

Unfortunately, your alert was not created at this time. Please try again.

Ok Ok

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

Create PhD Alert

Create Job Alert

When you create this PhD alert we will email you a selection of PhDs matching your criteria.When you create this job alert we will email you a selection of jobs matching your criteria. Our Terms and Conditions and Privacy Policy apply to this service. Any personal data you provide in setting up this alert is processed in accordance with our Privacy Notice

 
 
More jobs from The Institute of Cancer Research

Show all jobs for this employer …

More jobs like this
Join in and follow us

Browser Upgrade Recommended

jobs.ac.uk has been optimised for the latest browsers.

For the best user experience, we recommend viewing jobs.ac.uk on one of the following:

Google Chrome Firefox Microsoft Edge