Location: | London, South Kensington |
---|---|
Salary: | £48,056 to £56,345 per annum |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 7th November 2024 |
---|---|
Closes: | 4th December 2024 |
Job Ref: | NAT01855 |
Location: South Kensington Campus
About the role:
We are looking to recruit two talented and motivated Research Associates to join the group of Dr. Michalis Barkoulas in the Department of Life Sciences at the South Kensington Campus of Imperial College London.
This is part of a Wellcome Trust-funded project focusing on understanding how C. elegans senses and defends against some newly discovered natural eukaryotic pathogens that belong to the oomycete group. You will be expected to primarily carry out independent and collaborative research on host-pathogen interactions. You will also contribute to other activities in the lab, such as undergraduate and postgraduate student supervision and public outreach events. The Department of Life Sciences is one of the top places in the UK for research intensity in Biological Sciences, with a particular strength in the area of infection and immunity.
Key References:
[1]. Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans. Grover M, Gang SS, Troemel ER, Barkoulas M. PLOS Biology 2024 Mar 11;22(3):e3002543. doi: 10.1371/journal.pbio.3002543.
[2]. A PAX6-regulated receptor tyrosine kinase pairs with a pseudokinase to activate immune defense upon oomycete recognition in C. elegans. Drury F., Grover M., Hintze M., Saunders J., Fasseas M.K., Constantinou C., Barkoulas M. PNAS 2023 Sep 26;120(39):e2300587120.
[3]. Fasseas MK, Grover M, Drury F, Essmann CL, Kaulich E, Schafer WR, Barkoulas M. Chemosensory Neurons Modulate the Response to Oomycete Recognition in Caenorhabditis elegans. Cell Reports 2021 Jan 12;34(2):108604.
[4]. Osman GA, Fasseas MK, Koneru SL, Essmann CL, Kyrou K, Srinivasan MA, Zhang, Sarkies P, Félix M-A and Barkoulas M. Natural infection of C. elegans by an oomycete reveals a new pathogen-specific immune response. Current Biology 2018 28, 640–648
What you would be doing:
What we are looking for:
Further Information
Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant.
If you require any further details on the role please contact: Michalis Barkoulas – m.barkoulas@imperial.ac.uk
Type / Role:
Subject Area(s):
Location(s):