Postdoctoral Fellow

Location: The Francis Crick Institute, Midland Road, London

Short summary

We are looking for a postdoctoral fellow interested in combining interdisciplinary approaches with excellent tractability of zebrafish heart to study a fundamental problem – how organ form and function emerge during development. The suitable candidate will use advanced microscopic techniques, image analysis, genetic manipulations, biophysical approaches and collaborate with theoreticians to address this fundamental problem. 

The interested candidate should be keen in pursuing collaborative research, should be a good team player and should convey clearly in their application why they are interested in the lab’s research program. 

The overarching goal of our lab is to study how functional organs are built to sustain life during embryonic development. This is a long-standing problem in biology with significant implications for tissue engineering and birth defects. To solve this fundamental problem, we use a well-suited model system, the developing zebrafish heart, as it is amenable to state-of-art optical, biophysical, genetic manipulations. We take a systems biology approach by integrating tools from tissue mechanics, developmental genetics, transcriptomics, biophysics and predictive theoretical modelling. Using these approaches, we dissect the morphogenesis of a complex organ like heart at exceptional details, in the physiological context of a living embryo. 

Key Responsibilities

The post holder should embody and demonstrate our core Crick values – bold, imaginative, open, dynamic and collegial. 

• Lead their own projects and contribute to other projects on a collaborative basis (both in the lab and with external collaborators)
• Providing specialist advice and share knowledge and expertise with the lab
• Develops new tools and techniques
• Guide and train PhD students and new lab members in their research
• Willingness to actively contribute to a productive and positive lab atmosphere 

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy. 

• If you are interested in applying for this role, please apply via our website.
• The closing date for applications is 15/12/2024
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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