Research Assistant

About Us

Dr Robin Dart is a recently appointed Clinical Senior Lecturer working in mucosal immunology and inflammatory bowel disease (IBD), with a particular focus on immune-epithelial interactions and development of clinical cohorts to study the dynamics of resolution in IBD. Trained in mucosal immunology in Professor Adrian Hayday’s laboratory, he has contributed important insights into the regulation of human γδ T cells in the human colon. As a clinical senior lecturer in experimental medicine he works between the gastroenterology department at Guy’s and St Thomas Hospital and the laboratory at the Centre for Inflammation Biology and Cancer Immunology (CIBCI). The work undertaken in this laboratory is exclusively on human tissues. 

CIBCI brings together academics, clinicians and trainees to work on clinically relevant cellular and molecular mechanisms of inflammation and tumour immunobiology. This creates a stimulating environment to develop, investigate and apply cutting-edge models and techniques, both experimental and computational, to advance the understanding of human inflammatory disease and cancer. Our projects include studies on tissue imaging, immune cell signalling, immunometabolism, wound healing, neuro-immune interactions, antigen processing and presentation, and innate and adaptive immune cell function, differentiation and regulation.

About the role

Applications are invited from motivated and enthusiastic individuals who would like to join a friendly and dynamic group working in translational mucosal immunology. The role will be focused on supporting research activities and the establishment and the running of the laboratory at the Centre for Inflammation Biology and Cancer Immunology.

The successful candidate will be required to process and maintain clinical study sample collections and undertake research into how γδ intraepithelial lymphocytes interact with the epithelium using co-culture systems and in vitro disease models. They will learn and develop in vitro culture techniques, processing samples for RNA sequencing and flow cytometric analysis. Core additional activities will be to help with organisational aspects of the laboratory, maintaining human tissue and laboratory inventories.

The research assistant will be expected  to maintain accurate records of performed experiments, to analyze and summarize research results, and will be supported in developing research plans and writing reports and manuscripts. They will be expected to prioritise work and meet deadlines, and fully participate in research group and departmental activities, and to contribute to their positive and inclusive research culture. 

This is a full time position, and you will be offered a fixed term contract until 31/12/26.

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:

Essential criteria

• MSc in Immunology or related subject with lab experience
• Experience in FACS/FlowJo
• Experience in tissue culture
• Organised, efficient with excellent time management
• Good communication and interpersonal skills
• Excellent record keeping

Desirable criteria

• Knowledge of R and/or other analysis tools
• Experience of working in human studies and required flexibility
• Analytical skills and able to self-critique own work
• RNA-seq/sc-RNA-seq

Downloading a copy of our Job Description

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the page. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Advert information