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Postdoctoral Research Fellow in Neurophysiology

UCL - Department of Pharmacology

Location: London
Salary: £43,124 to £51,610
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 4th November 2024
Closes: 2nd December 2024
Job Ref: B02-07935

About us

The Research Department of Pharmacology was founded in 1926 and developed a strong neuroscience core in the 1970s. This has since further widened in scope to include other biological systems and disease indications such as inflammatory and vascular diseases, obesity and clinical pharmacology. Research being conducted is diverse, ranging from; (i) fundamental discovery work in how the brain develops and functions, (2) cell and molecular biology techniques to further our understanding of various conditions such as Parkinson’s Disease, Alzheimer’s Disease, a range of paediatric neurometabolic diseases, nerve injury, (iii) translational research in gene therapy and tissue engineering and (iv) in silico and pharmacokinetic studies to develop drug dosing in patients. Staff are involved in curriculum development and teaching across all four years of the MPharm programme and the MSc in Experimental Pharmacology and Therapeutics. The department also host extensive research pr ogrammes involving many PhD students and postdoctoral fellows.

Further information about the School can be found on the website at http://www.ucl.ac.uk/pharmacy

About the role

Applications are invited for a postdoctoral research fellow to join the Shah laboratory (https://profiles.ucl.ac.uk/19244) at UCL School of Pharmacy.

This is a new exciting role funded by a multi-center 5 year MRC and MNDA programme grant to discern the effects of ALS/Fronto-temporal dementia (FTD) mutations on human neuron intrinsic and synaptic properties as well as neural network function.

The successful candidate will use electrophysiological recordings and/or advanced imaging techniques to understand the effects of ALS/FTD mutations on human IPSC neuron function.

Additional methodologies that will be employed include molecular biology approaches (such as qPCR), immunohistochemistry and multi-electrode arrays. Further, the successful candidate will have a unique opportunity to work with other laboratories at UCL and KCL as part of this multi-disciplinary collaborative project.

For more information about this role, please contact Professor Mala Shah ().

About you

The successful candidate should have or will shortly obtain a Ph.D. in neuroscience or related subject.

We are seeking a highly motivated, enthusiastic individual with a good understanding of neuronal intrinsic (ion channel) and synaptic physiology to join our laboratory.

Experience in making electrophysiological patch-clamp recordings from neurons and a good publication track record would be highly advantageous.

A job description and person specification can be accessed at the bottom of this page.

What we offer

As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:

Click here to find out more.

Our commitment to Equality, Diversity and Inclusion

We are committed to advancing gender equality within our department. You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/


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