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PhD Studentship: Investigating Genetic Markers and Mechanisms of CO Dehydrogenase Regulation in Response to Atmospheric Mercury

University of East Anglia - School of Biological Sciences

Qualification Type: PhD
Location: Norwich
Funding for: UK Students, EU Students, International Students
Funding amount: £19,237 p.a. for 2024/25
Hours: Full Time
Placed On: 17th October 2024
Closes: 8th January 2025
Reference: HERNÁNDEZ GARCÍA_UBIO25ARIES

Primary supervisor - Dr Marcela Hernández García 

Scientific Background 

Volcanic emissions are a natural source of mercury (Hg) to the atmosphere and Mt. Etna (Italy) is a major natural source of Hg to the Mediterranean region. Previous research has shown that Hg deposited on the low pH and organic-poor soils of Etna's south-eastern flank may not be retained, but instead released to groundwater or re-emitted to the atmosphere, indicating that the deposition of volcanic Hg has clear environment impacts. The potential for Hg to disrupt local ecosystems is particularly concerning, as it may alter microbial activity, including their capability to oxidise trace gases such as carbon monoxide (highly abundant at Etna volcano). This plays a crucial role in atmospheric chemistry and climate regulation. In this proposal, you will investigate if Hg affects the microbial communities and specifically their capability of oxidising trace gases, such as carbon monoxide.  

The project 

You will be answering these key questions: 1) How do bacterial communities in recently formed soils from Mt Etna utilise CO, and what specific metabolic pathways are involved? and 2) Does exposure to mercury influence the expression and activity of CO-dehydrogenase enzyme in bacteria isolated from Mt. Etna soils?  

To answer these questions, you will join sampling campaigns at Mt. Etna followed by soil incubations and trace-gases measurements. You will be trained in cutting-edge tools for isolation and identification of microbes, including whole genome sequencing, proteomics, metagenomics and bioinformatics. 

Training 

Specific training will include the cultivation of soil bacteria; quantitative PCR; amplicon-based sequencing (metagenetics); whole genome sequencing, (meta)genomic analysis and proteomics. You will present results at weekly lab meetings, departmental seminars, and at national and international conferences. 

Person specification 

We are looking for a pro-active, highly motivated student willing to join sampling campaigns at Etna Volcano in Italy. The successful candidate should have a strong background in Microbial, biochemistry, Soil or Environmental Sciences (Soil Microbiology, Environmental Microbiology, or similar). 

For further information, please visit www.aries-dtp.ac.uk

Funding Details

Additional Funding Information

ARIES is awaiting confirmation of funding under the BBSRC-NERC DLA award scheme, which is expected shortly. Funding for this studentship is subject to this confirmation and UKRI terms and conditions. Successful candidates who meet UKRI’s eligibility criteria will be awarded a fully-funded ARIES studentship of fees, maintenance stipend (£19,237 p.a. for 2024/25) and research costs.

A limited number of ARIES studentships are available to International applicants. Please note however that ARIES funding does not cover additional costs associated with relocation to, and living in, the UK.

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