Location: | Leeds |
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Salary: | £27,344 to £31,387 per annum |
Hours: | Full Time |
Contract Type: | Fixed-Term/Contract |
Placed On: | 7th October 2024 |
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Closes: | 1st November 2024 |
Job Ref: | FBSMB1289 |
Are you an early career researcher looking for a challenge? Do you have a background in virology? Do you want to further your career in one of the UK’s leading research intensive Universities?
An exciting opportunity is available to join the laboratory of Dr Morgan Herod to study mechanisms of hepatitis E virus (HEV) replication, funded by the Medical Research Council. You will use a range of molecular virology approaches to study proteolytic processing of the HEV polyprotein. We recently made the exciting discovery that the polyprotein of HEV is not processed by a viral protease, thus implicating a host protease as critical in controlling viral replication. This position will build on these results and focus on identifying and characterising the role of host proteases in HEV replication, and define the role for HEV polyprotein domains in the virus lifecycle. The position provides an opportunity to conduct ground-breaking research into virus-host interactions and generate a new paradigm for RNA virus replication. To achieve this, it will exploit recently developed HEV culture and replicon systems, to conduct a functional proteomic analysis.
You will have a background in molecular biology and expertise in the study of viruses. You will join a team of researchers focusing on mechanisms of positive strand RNA virus replication and host-cell interactions. You will be organised and willing to work collaboratively as part of a team.
Please note that due to Home Office visa requirements, this role is not suitable for first-time Skilled Worker visa applicants. Information on other visa options is available at: https://www.gov.uk/browse/visas-immigration/work-visas
What we offer in return
And much more!
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