Research Associate

We are seeking to appoint an experienced Research Associate to work within an MRC funded project on mitochondrial biology in parasites.

The role is split between the School of Infection and Immunity, University Of Glasgow under the supervision of Professor Lilach Sheiner lilachsheiner.wixsite.com/sheinerlab-wtcmp and The University of Cambridge under the supervision of Professor Julian Rayner www.cimr.cam.ac.uk/staff/professor-julian-rayner-fmedsci. Successful candidate will be expected to spend a long period of time in one city and then in the other (likely starting at Cambridge).

Expected start date: 15/01/2025

The purpose of this role is to carry out cutting-edge research to understand mitochondrial biology in Plasmodium falciparum, the major cause of malaria mortality. The first and main core approach will be to carry out CRISPR/Cas9-guided experimental genetic modification of genes encoding mitochondrial proteins to create lines in which individual (or multiple) genes are tagged or deleted.

You will design and generate the vectors needed to modify the P. falciparum genome, transfect and genotype modified lines, and phenotype them using an array of cell-biology and biochemical approaches.

A secondary approach that might compose a “side project” is large scale culturing and biochemical isolation of mitochondria and/or mitochondrial complexes.

Your primary focus will be on carrying out outstanding academic research leading to impactful papers, providing substantial scope for innovation, creativity and scientific judgement. You will work as part of two highly collaborative teams, and particularly closely with another team member carrying out synergistic biochemical and structural work on the same topic, so collaboration, communication and collegiality are key attributes.

Informal enquiries should be directed to Professor Sheiner via email lilach.sheiner@glasgow.ac.uk

This post is full time and has funding until 14^th January 2028.

To apply online at: my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.jobspec?p_id=154710

We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community www.gla.ac.uk/myglasgow/humanresources/equalitydiversity.

We endorse the principles of Athena Swan www.gla.ac.uk/myglasgow/humanresources/equalitydiversity/athenaswan and hold bronze, silver and gold awards across the University.

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