Research Associate in Proteomics and Transporter Kinetics

Job reference: BMH-026303

Salary: £36,024 - £39,347 per annum, subject to qualifications and experience

Faculty/Organisational Unit: Biology, Medicine Health

Location: Manchester

Employment type: Fixed Term

Division/Team: Division of Pharmacy and Optometry

Hours Per Week: 1.0 FTE

Closing date (DD/MM/YYYY): 29/08/2024

Contract Duration: Fixed term period of 24 months

School/Directorate: School of Health Sciences

Applications are invited for a Research Associate in Proteomics and Transporter Kinetics, at the Centre for Applied Pharmacokinetic Research (CAPKR) of the Division of Pharmacy and Optometry. The post is full time and will be tenable on a fixed term basis of 24 months. The post-doctoral research associate will conduct research to understand local disposition of antibody drug conjugates and oligonucleotides in samples mainly using proteomics approaches and in-depth data analysis, that will allow development of PBPK models to predict drug concentration at the site of action for a more accurate PKPD prediction.

Successful candidate will become a member of the CAPKR research team and be fully involved in a project entitled “Defining Local Disposition Beyond What is Known for Small Molecules to Assist Building PBPK Framework for Oligonucleotide and Antibody Drug Conjugate Modalities”.  The applicant should hold a PhD in a biomedical, systems biology, pharmaceutical, systems modelling or a similar research area, and have experience with at least some of the techniques: sample preparation, proteomics, enzyme and transporter kinetics and cell based and cell fraction models. In addition, experience in transcriptomic and proteomic analyses is required. Previous experience of mathematical modelling using relevant software packages would be desirable.

What can you expect in return

The University will actively foster a culture of inclusion and diversity and will seek to achieve true equality of opportunity for all members of its community.

What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

Closing date: 29th August 2024

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status.  All appointments are made on merit.

Our University is positive about flexible working – you can find out more here

Hybrid working arrangements may be considered.           

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.

Any recruitment enquiries from recruitment agencies should be directed to People.Recruitment@manchester.ac.uk.

Any CV’s submitted by a recruitment agency will be considered a gift.

Enquiries about the vacancy, shortlisting and interviews:

Email: Prof. Amin Rostami (amin.rostami@manchester.ac.uk) or Dr. Sayema Rahman Khan (Sayema.khan@manchester.ac.uk)

General enquiries:

Email: People.recruitment@manchester.ac.uk

Technical support:

https://jobseekersupport.jobtrain.co.uk/support/home

This vacancy will close for applications at midnight on the closing date.

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