Senior Research Associate in Structural Biology

The role

The Berger team is seeking to fill a BBSRC-funded senior Post-doctoral Research Associate post (Grade J) at the School of Biochemistry, University of Bristol UK. You will drive world-class structural biology research to decipher the structure and mechanism of the transcription pre-initiation complex (PIC) in the growing oocyte, and use an integrated approach to elucidate this fundamental biological process of gene expression combining cutting edge cryo-electron microscopy (cryo-EM), biochemical and biophysical techniques.

You will be working closely with our international collaborators the IGBMC in Strasbourg, France, The University of Regensburg, Germany, and the University of Colorado, Boulder, USA.

You will participate in a vibrant and dynamic, inclusive and equitable research environment in a laboratory developing and applying cutting edge technology to generate new knowledge and biological insights in a top 10 UK University, in one of the best cities to live in the UK.

What will you be doing?

You will be part of a leading research team deploying structural techniques including cryo-EM, biophysical and biochemical methods to uncover fundamental mechanisms of gene expression at the core of development, reproduction and infertility. Showing a high degree of independence, you will drive an ambitious research programme, synergizing with your colleagues in the Berger team and our world-class collaborators, using cutting edge technologies.  For information about the Berger lab and our research activities please follow:  https://www.linkedin.com/in/imre-berger-7a0a6a50/, https://scholar.google.co.uk/citations?user=pzEPqLoAAAAJ&hl=en)

You should apply if

• Enjoy working on a cutting-edge project in structural, molecular and cell biology
• Are a dedicated team player in an international, dynamic, diverse and equitable team
• Have a keen interest in fundamental mechanisms of gene expression relevant to development, reproduction and infertility/
• Are independent and resourceful and excited about basic research and fundamental discoveries
• Have demonstrated experience with eukaryotic tissue culture work, cryo-EM, molecular biology, biophysical and biochemical techniques and recombinant production and purification of eukaryotic proteins and the reconstitution and analysis of protein/DNA complexes.

Additional information

For informal queries about the role please contract: Prof Imre Berger at imre.berger@bristol.ac.uk

This advert will close at 23:59 UK time on Wednesday 24th of July 2024

Our strategy and mission

We recently launched our strategy to 2030 tying together our mission, vision and values.

The University of Bristol aims to be a place where everyone feels able to be themselves and do their best in an inclusive working environment where all colleagues can thrive and reach their full potential. We want to attract, develop, and retain individuals with different experiences, backgrounds and perspectives – particularly people of colour, LGBT+ and disabled people - because diversity of people and ideas remains integral to our excellence as a global civic institution.

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