Postdoctoral Research Sceintist

Full-time, Fixed term until 03 July 2027

Applications are invited for a Post-Doctoral neuronal cell biologist to work on a project to target calcium channels in Parkinson’s disease. The project, funded by the Michael J Fox Foundation and in collaboration with Lario Therapeutics, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. This work will develop new inhibitors of calcium channels as a neuroprotective strategy to protect vulnerable dopamine neurons in Parkinson’s working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson’s patients.

Duties include growth and differentiation of iPSC lines; leading on design and implementation of experiments and cellular assays in neurobiology (eg: calcium imaging, multi-electrode array (MEA), biochemistry, immunocytochemistry, cell and molecular biology; interpretation of data; preparation of data for publication; contribute ideas for new research projects and develop ideas for generating research income; manage own academic research involving small-scale project management; supervise a Research Assistant on the project; and act as a source of information to other members of the group. 

You will have excellent knowledge relating to neurodegenerative disease and practical experience in neuronal cell culture and in techniques relevant to molecular and cellular neuroscience. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is also essential. Applicants must hold, or be near completion of, a PhD/DPhil in a relevant area of research and have experience in cellular neuroscience, and molecular cell biology relevant to analysis of neuronal phenotypes.

The post is available immediately until 03 July 2027. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford.

Informal enquiries may be directed Professor Richard Wade-Martins (richard.wade-martins@dpag.ox.ac.uk).

Closing date for applications is midday on Monday 12 August 2024. Interviews are likely to be held the week beginning 26 August 2024.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.  

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion

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