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Research Assistant

University of Oxford - Department of Physiology

Location: Oxford
Salary: £32,332 to £34,980
Hours: Full Time
Contract Type: Fixed-Term/Contract
Placed On: 15th July 2024
Closes: 12th August 2024
Job Ref: 174160

Full-time, Fixed term until 03 July 2027

Applications are invited for a Research Assistant neuronal cell biologist to work on a project to target calcium channels in Parkinson’s disease. The project, funded by the Michael J Fox Foundation and in collaboration with Lario Therapeutics, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. This work will develop new inhibitors of calcium channels as a neuroprotective strategy to protect vulnerable dopamine neurons in Parkinson’s working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson’s patients.

Duties will include undertaking laboratory experiments; biochemistry, immunocytochemistry, cell and molecular biology; growth and differentiation of iPSC lines; interpretation of data; imaging analysis; and preparation of data for publication. You will have excellent practical experience of working with neuronal cell cultures and good knowledge of cellular models of neurodegenerative disease. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.  

Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.

The post is available immediately and runs until 03 July 2027. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford, OX1 3QU

Informal enquiries may be directed Professor Richard Wade-Martins (richard.wade-martins@dpag.ox.ac.uk).

Closing date for applications is midday on Monday 12th August 2024. Interviews are likely to be held in the week commencing 26th August 2024.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.  

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion

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