Postdoctoral Fellow - Cell Fate and Gene Regulation Group

Location: The Francis Crick Institute, Midland Road, London

Short summary

An exciting opportunity to be part of a pioneering biomedical research institute, dedicated to innovation and science. A postdoctoral research post in the laboratory of Folkert van Werven to study Transcription/RNA biology is now available. We are looking for a highly motivated researcher in with a strong affinity for molecular biology and biochemistry, but also candidates with backgrounds in genomics, genetics, and computational biology will be considered. The exact project will be formulated together with the candidate, but is likely on the interface of transcription, noncoding RNAs, and RNA modifications. We use budding yeast and mammalian in vitro cell culture systems as model.

The Project

The laboratory of Folkert van Werven uses budding yeast and mammalian cells to study how RNA expression is regulated when cells change from one state to another. Specifically, we have focused on understanding the roles of transcription, transcript heterogeneity including noncoding RNAs, RNA isoforms, and RNA modifications.

Details of research projects currently being undertaken can be seen at: https://www.crick.ac.uk/research/labs/folkert-van-werven. Research techniques used in the laboratory include: basic techniques of biochemistry, molecular biology, various genomic approaches, genetics, and microscopy. Postdoctoral Training Fellows are expected to lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators). The ability to work in a team is essential.

Postdoctoral Fellows will lead their own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential. Noteworthy is that the group of Folkert van Werven will move before the spring of 2027, and the postdoctoral fellow is expected to move with the group.

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy. 

• If you are interested in applying for this role, please apply via our website.
• The closing date for applications is 31/08/2024
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

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